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| Status |
Public on Aug 01, 2021 |
| Title |
Expression data from 3-month-old mouse hippocampus of Ts1Cje and wild-type mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
The Ts1Cje mouse model of Down syndrome (DS) has partial triplication of mouse chromosome 16, of which a large portion is homologous to human chromosome 21. The mouse model shows an impaired neurogenesis in hippocampus at 3-month-old . We analyzed the effect of Ts1Cje trisomic region on global gene expression in the adult brain of Ts1Cje mice at 3-month-old.
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| Overall design |
RNA was extracted from hippocampus for hybridization to arrays from 4 pairs of Ts1Cje and disomic wild-type littermate control.
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| Contributor(s) |
Ishihara K |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Oct 27, 2020 |
| Last update date |
Aug 02, 2021 |
| Contact name |
Keiichi Ishihara |
| E-mail(s) |
ishihara@mb.kyoto-phu.ac.jp
|
| Phone |
+81-75-595-4656
|
| Organization name |
Kyoto Pharmaceutical University
|
| Department |
Department of Pathological Biochemistry
|
| Street address |
5 Misasagi Nakauchi-cho, Yamashina-ku
|
| City |
Kyoto |
| State/province |
Kyoto |
| ZIP/Postal code |
6078414 |
| Country |
Japan |
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| Platforms (1) |
| GPL13912 |
Agilent-028005 SurePrint G3 Mouse GE 8x60K Microarray (Feature Number version) |
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| Samples (8)
|
| GSM4862031 |
SAMPLE 1: hippocampus_wild-type_3-month-old_replicate1 |
| GSM4862032 |
SAMPLE 2: hippocampus_Ts1Cje_3-month-old_replicate1 |
| GSM4862033 |
SAMPLE 3: hippocampus_wild-type_3-month-old_replicate2 |
| GSM4862034 |
SAMPLE 4: hippocampus_Ts1Cje_3-month-old_replicate2 |
| GSM4862035 |
SAMPLE 5: hippocampus_wild-type_3-month-old_replicate3 |
| GSM4862036 |
SAMPLE 6: hippocampus_Ts1Cje_3-month-old_replicate3 |
| GSM4862037 |
SAMPLE 7: hippocampus_wild-type_3-month-old_replicate4 |
| GSM4862038 |
SAMPLE 8: hippocampus_Ts1Cje_3-month-old_replicate4 |
|
| Relations |
| BioProject |
PRJNA672281 |
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