 |
 |
GEO help: Mouse over screen elements for information. |
|
| Status |
Public on Nov 05, 2020 |
| Title |
Differential plasma exosomal long non-coding RNAs expression profiles and their emerging role in E-cig users, cigarette, waterpipe and dual smokers |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
Non-coding RNA profiling by array
|
| Summary |
Long non-coding RNA (lncRNA) are the varied set of transcripts that are known to play a critical role in biological processes like gene regulation, transcription, post-transcriptional modification, and chromatin remodeling.
Recent studies have reported the presence of lncRNA in the exosomes and have proven their involvement in regulating cell-to-cell communication in lung pathologies including lung cancer, chronic obstructive pulmonary disease (COPD), asthma, and idiopathic pulmonary fibrosis (IPF).
|
| |
|
| Overall design |
In this study, we compared the lncRNA profiles in the plasma-derived exosomes amongst non-smokers (NS), cigarette smokers (CS), E-cig users (E-cig), waterpipe smokers (WP) and dual smokers (CSWP) using GeneChip™ WT Pico kit for transcriptional profiling.
|
| |
|
| Contributor(s) |
Kaur G, Singh K, Maremanda KP, Li D, Chand HS, Rahman I |
| Citation(s) |
33290406 |
| Submission date |
Nov 03, 2020 |
| Last update date |
Feb 05, 2021 |
| Contact name |
Irfan Rahman |
| E-mail(s) |
Irfan_Rahman@URMC.Rochester.edu
|
| Phone |
2252887259
|
| Organization name |
University of Rochester Medical Center
|
| Department |
Environmental Medicine
|
| Lab |
Lung Biology Lab
|
| Street address |
601 elmwood ave
|
| City |
Rochester |
| State/province |
NY |
| ZIP/Postal code |
14620 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL23126 |
[Clariom_D_Human] Affymetrix Human Clariom D Assay [transcript (gene) version] |
|
| Samples (30)
|
| GSM4878944 |
Non-smoker, exoRNA_batch1_biological rep 1 |
| GSM4878945 |
Non-smoker, exoRNA_batch1_biological rep 2 |
| GSM4878946 |
Non-smoker, exoRNA_batch1_biological rep 3 |
| GSM4878947 |
Cigarette Smoker, exoRNA_batch1_biological rep 1 |
| GSM4878948 |
Cigarette Smoker, exoRNA_batch1_biological rep 2 |
| GSM4878949 |
Cigarette Smoker, exoRNA_batch1_biological rep 3 |
| GSM4878950 |
E-cig Vaper, exoRNA_batch1_biological rep 1 |
| GSM4878951 |
E-cig Vaper, exoRNA_batch1_biological rep 2 |
| GSM4878952 |
E-cig Vaper, exoRNA_batch1_biological rep 3 |
| GSM4878953 |
Waterpipe user, exoRNA_batch1_biological rep 1 |
| GSM4878954 |
Waterpipe user, exoRNA_batch1_biological rep 2 |
| GSM4878955 |
Waterpipe user, exoRNA_batch1_biological rep 3 |
| GSM4878956 |
Dual Smoker, exoRNA_batch2_biological rep 1 |
| GSM4878957 |
Dual Smoker, exoRNA_batch2_biological rep 2 |
| GSM4878958 |
Dual Smoker, exoRNA_batch2_biological rep 3 |
| GSM4878959 |
Dual Smoker, exoRNA_batch2_biological rep 4 |
| GSM4878960 |
Dual Smoker, exoRNA_batch2_biological rep 5 |
| GSM4878961 |
Dual Smoker, exoRNA_batch2_biological rep 6 |
| GSM4878962 |
Cigarette Smoker, exoRNA_batch2_biological rep 4 |
| GSM4878963 |
Cigarette Smoker, exoRNA_batch2_biological rep 5 |
| GSM4878964 |
Cigarette Smoker, exoRNA_batch2_biological rep 6 |
| GSM4878965 |
Non-smoker, exoRNA_batch2_biological rep 4 |
| GSM4878966 |
Non-smoker, exoRNA_batch2_biological rep 5 |
| GSM4878967 |
Non-smoker, exoRNA_batch2_biological rep 6 |
| GSM4878968 |
Waterpipe user, exoRNA_batch2_biological rep 4 |
| GSM4878969 |
Waterpipe user, exoRNA_batch2_biological rep 5 |
| GSM4878970 |
Waterpipe user, exoRNA_batch2_biological rep 6 |
| GSM4878971 |
E-cig Vaper, exoRNA_batch2_biological rep 4 |
| GSM4878972 |
E-cig Vaper, exoRNA_batch2_biological rep 5 |
| GSM4878973 |
E-cig Vaper, exoRNA_batch2_biological rep 6 |
|
| Relations |
| BioProject |
PRJNA674382 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE160769_All_Processed_data.xlsx |
32.2 Mb |
(ftp)(http) |
XLSX |
| GSE160769_RAW.tar |
573.9 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
| Processed data are available on Series record |
|
|
|
|
 |
Less...
More...