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| Status |
Public on Nov 25, 2021 |
| Title |
Neuronal development in NEIL3-deficient mice (hippocampus) |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
brain tissue from all subregions (CA1, CA3, dentate gyrus) of the hippocampal formation was isolated at postnatal day 8 and at an adult age (3-6months old animals) in wildtype and NEIL3-deficient mice (n=4 at p8 and n=3 at adult age). NEILs are DNA glycosylases potentially involved in transcription regulation and hippocampal neuronal maturation. RNA was extracted and sequenced.
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| Overall design |
Wildtype (C57Bl6) and mice deficient in NEIL3 (C57Bl6-background) were used. Tissue was isolated exclusively at baseline, i.e. the animal was taken directly from its homecage without any behavioral intervention
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| Contributor(s) |
Kunath N, Obermann T, Bugaj A, Fernandez MS, Bjørås M, Ye J |
| Citation(s) |
34988395 |
| Submission date |
Nov 09, 2020 |
| Last update date |
Oct 02, 2023 |
| Contact name |
Jing Ye |
| E-mail(s) |
jing.ye@ntnu.no
|
| Organization name |
Norwegian University of Science and Technology (NTNU)
|
| Department |
Department of Clinical and Molecular Medicine (IKOM)
|
| Street address |
Høgskoleringen 1
|
| City |
Trondheim |
| ZIP/Postal code |
7030 |
| Country |
Norway |
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| Platforms (1) |
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| Samples (42)
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| This SuperSeries is composed of the following SubSeries: |
| GSE175358 |
Neuronal development in NEIL3-deficient mice (hippocampus) [CA1] |
| GSE175359 |
Neuronal development in NEIL3-deficient mice (hippocampus) [CA3] |
| GSE175360 |
neuronal development in NEIL3-deficient mice (hippocampus) [DG] |
|
| Relations |
| BioProject |
PRJNA675494 |
| SRA |
SRP291697 |
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