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| Status |
Public on Jan 16, 2021 |
| Title |
Gene expression analysis in HeLa Kyoto cells upon knockdown of JAZF1 |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
The goal was the investigation of JAZF1's possible role in regulating gene expression. RNA-seq analysis revealed that depletion of JAZF1 results in transcriptome changes that affect, among others, ribosome biogenesis.
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| Overall design |
Gene expression profiles of HeLa Kyoto cells upon knockdown of JAZF1 compared to control treatment (with biological replicates) were generated by RNA-sequencing
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| Contributor(s) |
Friedrich T, Bartkuhn M, Procida T |
| Citation(s) |
33445503 |
| Submission date |
Dec 14, 2020 |
| Last update date |
Jan 18, 2021 |
| Contact name |
Tobias Friedrich |
| E-mail(s) |
tobias.friedrich@biochemie.med.uni-giessen.de
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| Organization name |
Justus-Liebig-University
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| Department |
Institute of Biochemistry
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| Street address |
Friedrichstr. 24
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| City |
Giessen |
| ZIP/Postal code |
35392 |
| Country |
Germany |
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| Platforms (1) |
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| Samples (10)
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| GSM4975190 |
RNA-seq of HeLa Kyoto cells treated with control siRNA pool, 1. Replicate, Batch one |
| GSM4975191 |
RNA-seq of HeLa Kyoto cells treated with JAZF1 siRNA pool, 1. Replicate, Batch one |
| GSM4975192 |
RNA-seq of HeLa Kyoto cells treated with control siRNA pool, 2. Replicate, Batch one |
| GSM4975193 |
RNA-seq of HeLa Kyoto cells treated with JAZF1 siRNA pool, 2. Replicate, Batch one |
| GSM4975194 |
RNA-seq of HeLa Kyoto cells treated with control siRNA pool, 3. Replicate, Batch two |
| GSM4975195 |
RNA-seq of HeLa Kyoto cells treated with JAZF1 siRNA pool, 3. Replicate, Batch two |
| GSM4975196 |
RNA-seq of HeLa Kyoto cells treated with control siRNA pool, 4. Replicate, Batch two |
| GSM4975197 |
RNA-seq of HeLa Kyoto cells treated with JAZF1 siRNA pool, 4. Replicate, Batch two |
| GSM4975198 |
RNA-seq of HeLa Kyoto cells treated with control siRNA pool, 5. Replicate, Batch two |
| GSM4975199 |
RNA-seq of HeLa Kyoto cells treated with JAZF1 siRNA pool, 5. Replicate, Batch two |
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| Relations |
| BioProject |
PRJNA685204 |
| SRA |
SRP297944 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE163214_RAW.tar |
1.3 Mb |
(http)(custom) |
TAR (of CSV) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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