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| Status |
Public on Jul 02, 2009 |
| Title |
Bio-electrospraying the nematode Caenorhabditis elegans |
| Organism |
Caenorhabditis elegans |
| Experiment type |
Expression profiling by array
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| Summary |
Bio-electrospray, the direct jet-based cell handling apporach, is able to handle a wide range of cells. Studies at the genomic, genetic, and the physiological level have shown that, post-treatment, cellular integrity is unperturbed and a high percentage (>70%, compared to control) of cells remain viable. Although, these results are impressive, it may be argued that cell based systems are oversimplistic. This study utilizing a well characterised multicellular model organism, the non-parasitic nematode Caenorhabditis elegans. Nematodes were subjected to bio-electrosprays to demonstrate that bio-electrosprays can be safely applied to nematodes.
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| Overall design |
The global transcriptomic response was compared in control nematodes (negative control), heat shocked nematodes (positive control). and nematodes subjected to bio-electrospray.
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| Contributor(s) |
Mongkoldhumrongkul N, Swain SC, Jayasinghe SN, Sturzenbaum SR |
| Citation(s) |
19776148 |
| Submission date |
Jul 01, 2009 |
| Last update date |
Jul 06, 2016 |
| Contact name |
Stephen Sturzenbaum |
| E-mail(s) |
stephen.sturzenbaum@kcl.ac.uk
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| Organization name |
King's College London
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| Department |
Analytical, Environmental and Forensic Sciences
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| Street address |
150 Stamford Street
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| City |
London |
| ZIP/Postal code |
SE1 9NH |
| Country |
United Kingdom |
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| Platforms (1) |
| GPL200 |
[Celegans] Affymetrix C. elegans Genome Array |
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| Samples (3) |
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| Relations |
| BioProject |
PRJNA117707 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE16915_RAW.tar |
4.6 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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