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Series GSE16921 Query DataSets for GSE16921
Status Public on Sep 20, 2010
Title Polymorphic cis- and trans-regulation of human gene expression
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Expression levels of human genes vary extensive among individuals. Gene expression determines cell function and characteristics thus this variation likely contributes to phenotypic variation. Genetic studies have shown that there is a heritable component to gene expression variation, and have identified genomic regions that contain polymorphic regulators. However, most of these regions are quite large, and few regulators have been identified. In this genetic of gene expression study, we used a large sample to search the genome for polymorphic regulators that influence gene expression, and followed up the results with deep sequencing of transcriptomes and molecular analyses.
Key word(s): Transcriptome Analysis
 
Overall design genetics of gene expression study, 41 Coriell cell line samples examined.
 
Contributor(s) Morley M, Cheung VG
Citation(s) 20856902, 22019781
Submission date Jul 01, 2009
Last update date May 15, 2019
Contact name Michael Patrick Morley
E-mail(s) mmorley@pennmedicine.upenn.edu
Phone 215-898-2026
Organization name Perelman School of Medicine at the University of Pennsylvania
Department Penn Cardiovascular Institute
Street address 3400 Civic Center Blvd, Bldg 421
City Philadelphia
State/province PA
ZIP/Postal code 19104
Country USA
 
Platforms (1)
GPL9052 Illumina Genome Analyzer (Homo sapiens)
Samples (41)
GSM424320 GM06985_RNAseq
GSM424321 GM06993_RNAseq
GSM424322 GM06994_RNAseq
Relations
SRA SRP001563
BioProject PRJNA117631

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE16921_RAW.tar 51.3 Gb (http)(custom) TAR (of MAP, TXT)
SRA Run SelectorHelp
Processed data provided as supplementary file
Raw data are available in SRA

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