|
| Status |
Public on Jun 01, 2021 |
| Title |
Genome-wide analysis of SHOX targets in NHDF cells expressing SHOX WT vs SHOX HM mutant |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
To elucidate the underlying molecular mechanisms and to better understand the broad phenotypic spectrum of SHOX deficiency, we aimed to identify novel SHOX targets. We analyzed differentially expressed genes in SHOX-overexpressing human fibroblasts (NHDF)
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| |
|
| Overall design |
Total RNA obtained from SHOX WT and SHOX HM overexpressing NHDF cells after 6,12 and 24 hours of transfection
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| |
|
| Contributor(s) |
Hoffmann S, Roeth R |
| Citation(s) |
34122528 |
| Submission date |
Mar 26, 2021 |
| Last update date |
Jun 25, 2021 |
| Contact name |
Sandra Hoffmann |
| Organization name |
University of Heidelberg
|
| Department |
Human Molecular Genetics
|
| Street address |
Im Neuneheimer Feld 366
|
| City |
Heidelberg |
| ZIP/Postal code |
69120 |
| Country |
Germany |
| |
|
| Platforms (1) |
| GPL6104 |
Illumina humanRef-8 v2.0 expression beadchip |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA717783 |
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