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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Jul 15, 2010 |
| Title |
Gene Expression upon Doxorubicin Treatments |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Murine C26 tumor xenografts displayed different responses to the treatments of PBS, Doxorubicin (Dox), and chimeric polypeptide (CP)-Dox conjugates. We used microarrays to globally study gene expression underlying these different responses and identified distinct classes of up-regulated or down-regulated genes upon treatment.
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| Overall design |
C26 murine colon carcinoma xenografts were analyzed at 48 hours after treatment with CP-Dox, free Dox, and PBS (control). This study involved four replicates of each treatment.
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| Contributor(s) |
McDaniel JR, MacKey JA, Chen M, Chilktoi A |
| Citation(s) |
19898461 |
| Submission date |
Jul 15, 2009 |
| Last update date |
May 04, 2018 |
| Contact name |
ASHUTOSH CHILKOTI |
| E-mail(s) |
chilkoti@duke.edu
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| Organization name |
Duke University
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| Department |
BME
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| Lab |
Chilkoti
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| Street address |
BME, PO Box 90281, Duke University
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| City |
Durham |
| State/province |
NC |
| ZIP/Postal code |
27708 |
| Country |
USA |
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| Platforms (1) |
| GPL8321 |
[Mouse430A_2] Affymetrix Mouse Genome 430A 2.0 Array |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA119829 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE17115_RAW.tar |
24.2 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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