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Series GSE171740 Query DataSets for GSE171740
Status Public on Apr 09, 2021
Title Intrapericardial administration of secretomes from endometrial-derived mesenchymal stromal cells: effects on immune-related genes in a porcine model of myocardial infarction
Organism Sus scrofa
Experiment type Expression profiling by array
Summary Using a porcine model of acute myocardial infarction, we explored the potential effect of secretomes from endometrial-derived mesenchymal stromal cells (endMSCs) and from IFNγ/TNFα-primed endMSCs on immune-related genes in the infarcted tissue.
 
Overall design Infarcted tissues from pigs administered with placebo (n = 4), secretomes from endometrial mesenchymal stromal cells (S-enMSCs) (n = 4), and secretomes from IFNγ/TNFα-primed  endometrial derived  mesenchymal stromal cells (S-enMSCs*) were collected at 7 days post-therapy for RNA extraction and Affymetrix microarrays. Differentially gene expression analysis between biogroups were performed and immuno-related genes were determined.
 
Contributor(s) López Nieto E, García Casado J
Citation(s) 35625854
Submission date Apr 08, 2021
Last update date Jun 01, 2022
Contact name Juan Carlos Silla-Castro
Organization name CNIC
Department Bioinformatics
Street address Melchor Fernandez Almagro 3
City Madrid
ZIP/Postal code 28029
Country Spain
 
Platforms (1)
GPL18699 [PorGene-1_1-st] Porcine Gene 1.1 ST Array [transcript (gene) version]
Samples (12)
GSM5233174 AMI/Placebo, rep1
GSM5233175 AMI/Placebo, rep2
GSM5233176 AMI/Placebo, rep3
Relations
BioProject PRJNA720692

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE171740_RAW.tar 48.2 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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