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| Status |
Public on Dec 31, 2018 |
| Title |
Activation dependent gene expression in Treg cells compared to various inhibitory factors |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Regulatory T (Treg) cells are involved in self tolerance and suppression of immunity to pathogens or tumours. FOXP3 is essential for Treg cell development and function. However, the FOXP3-dependent molecular mechanisms are not well understood. Here we compare the expression levels in CD4+ as well as Treg cells in reponse to different treatments in order to evaluate the Treg cell specific gene expression profile.
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| Overall design |
Freshly isolated CD4+ T cells, CD4+CD25- as well as CD4+CD25+ Treg cells were treated as indicated and afterwards analysed by perfoming genome-wide expression analysis.
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| Contributor(s) |
Chemnitz J, Beyer M, Schultze J |
| Citation missing |
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| Submission date |
Jul 20, 2009 |
| Last update date |
Dec 31, 2018 |
| Contact name |
Joachim Schultze |
| E-mail(s) |
j.schultze@uni-bonn.de
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| Organization name |
LIMES (Life and Medical Sciences Center Genomics and Immunoregulation)
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| Department |
Genomics and Immunoregulation
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| Street address |
Carl-Troll-Strasse 31
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| City |
Bonn |
| State/province |
NRW |
| ZIP/Postal code |
53115 |
| Country |
Germany |
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| Platforms (1) |
| GPL2507 |
Sentrix Human-6 Expression BeadChip |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA119227 |
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