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Series GSE172491 Query DataSets for GSE172491
Status Public on Apr 22, 2021
Title Regulation of adipocyte differentiation by IRF3
Organism Mus musculus
Experiment type Expression profiling by array
Summary The hypothesis tested is that IRF3 regulates adipogenesis and adipocyte function. Global gene expression of IRF3 wildtype (WT) and knockout (KO) adipocytes at different days during differentiation was compared. The results provide evidence on how IRF3 controls PPARg -regulated adipogenic program thereby regulate adipocyte differentiation.
Overall design IRF3 WT and KO preadipocytes were isolated from white adipose tissue for differentation. Cells were harvested at day 3, 5, 7 and 9 during differentiation to isolate RNA for microarray analysis.
Contributor(s) Zhang Y, Tang P, Yang H
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Submission date Apr 21, 2021
Last update date Apr 23, 2021
Contact name Henry Yang
Organization name Cancer Science Institute of Singapore
Street address 28 Medical Drive
City Singapore
ZIP/Postal code 117456
Country Singapore
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (8)
GSM5257934 Cell_wildtype_day3
GSM5257935 Cell_wildtype_day5
GSM5257936 Cell_wildtype_day7
BioProject PRJNA723554

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE172491_RAW.tar 3.1 Mb (http)(custom) TAR
GSE172491_non_normalized.txt.gz 900.1 Kb (ftp)(http) TXT
Raw data are available on Series record
Processed data included within Sample table

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