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Series GSE17388 Query DataSets for GSE17388
Status Public on Jul 29, 2009
Title Gene expression analysis of rat livers treated with pharmaceutical development compounds
Organism Rattus norvegicus
Experiment type Expression profiling by array
Summary We used microarrays to analyze gene expression changes in liver after treatment of rats with two compounds from drug development (R1, R2) to identify potential effects related to hepatotoxicity.
The development cpds have been described in:
Pierson et al., J Med Chem 52: 3855-62.
R1 corresponds to 36, R2 corresponds to 38
 
Overall design Compound R1 or R2, or vehicle control, was given for either 24h or 2 weeks (336h) at different doses.
 
Contributor(s) Roth A, Steiner G
Citation(s) 21671310
Submission date Jul 28, 2009
Last update date Feb 21, 2017
Contact name Adrian B Roth
Organization name Roche
Department NCS
Lab 90-518a
Street address Grenzacherstr 124
City Basel
ZIP/Postal code 4070
Country Switzerland
 
Platforms (1)
GPL85 [RG_U34A] Affymetrix Rat Genome U34 Array
Samples (44)
GSM434432 Liver Study1 24h Vehicle_Control dose 0 - rep 1
GSM434433 Liver Study1 24h Vehicle_Control dose 0 - rep 2
GSM434434 Liver Study1 24h Vehicle_Control dose 0 - rep 3
Relations
BioProject PRJNA118823

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE17388_RAW.tar 50.8 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
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