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| Status |
Public on May 15, 2021 |
| Title |
Difference between sulforaphane and sulforaphene in colon cancer |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Sulforaphane and sulforaphene are isothiocyanate compounds derived from cruciferous vegetables that have demonstrated antiproliferative properties against colon cancer. However, the underlying mechanism of action of these two compounds is yet to be elucidated.
The present study aimed to study the effects of sulforaphane and sulforaphene on colon cancer by next-generation sequencing (NGS).
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| Overall design |
The colon cancer cell line, SW480, was cultured with 25 μmol/l sulforaphane and sulforaphene. Total RNA was extracted following 48 h of incubation of the cells with the compounds and NGS was performed with Clariom S Array.
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| Contributor(s) |
Wang Y |
| Citation(s) |
34457045 |
| Submission date |
May 14, 2021 |
| Last update date |
Aug 30, 2021 |
| Contact name |
Fengying Du |
| E-mail(s) |
sdudfy@126.com
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| Organization name |
Shandong Provincial Hospital
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| Street address |
jingwuweiqi street, 324
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| City |
Jinan |
| State/province |
China |
| ZIP/Postal code |
250012 |
| Country |
China |
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| Platforms (1) |
| GPL23159 |
[Clariom_S_Human] Affymetrix Clariom S Assay, Human (Includes Pico Assay) |
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| Samples (9)
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| Relations |
| BioProject |
PRJNA729976 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE174444_RAW.tar |
9.1 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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