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Series GSE17662

Query DataSets for GSE17662

Status

Public on Sep 20, 2009

Title

Modulation of gene expression by rapamycin in hepatic cell lines, H5D and GN5

Organism

Rattus norvegicus

Experiment type

Expression profiling by array

Summary

Two rat hepatic cell lines, GN5 and H5D, were characterized for the effect of rapamycin on gene expression. These cells lines are tumorigenic and display intermediate sensitivity to the growth inhibitory effects of rapamycin. The goal of this experiment was to assess the effect of rapamycin on gene expression independent of effects on cell proliferation.

Overall design

Total RNA for each of four experimental groups was prepared and analyzed in triplicate: GN5, Vehicle Control; GN5, Rapamycin; H5D, Vehicle Control; H5D, Rapamycin

Contributor(s)

Jimenez RH, Boylan JM, Sanders JA, Gruppuso PA

Citation(s)

19816606

Submission date

Aug 14, 2009

Last update date

Jul 29, 2014

Contact name

Jennifer Ann Sanders

E-mail(s)

Jennifer_Sanders@brown.edu

Organization name

Rhode Island Hospital

Department

Pediatric Endocrinology

Street address

593 Eddy Street

City

Providence

State/province

ZIP/Postal code

02903

Country

USA

Platforms (1)

GPL6101

Illumina ratRef-12 v1.0 expression beadchip

Samples (12)

More...

GSM440892	H5D, Control, Rep1
GSM440893	H5D, Control, Rep2
GSM440894	H5D, Control, Rep3

This SubSeries is part of SuperSeries:

GSE17677

Modulation of gene expression by rapamycin in hepatic cell lines

Relations

BioProject

PRJNA123387

GN5R vs. GN5V: 1.2x and FDR<0.05 For gene expression comparisons, genes with expression values less than 100 or fold change less than 1.2 were excluded from further statistical analyses. A two-sample t-test using p-value cut-off of 0.05 with multiple test correction (Benjamini and Hochberg false discovery rate) was applied for each gene to determine if the gene were differentially expressed in the pair wise comparisons. Triplicate control and rapamycin samples from each cell line were used in these comparisons. header descriptions
Probe ID
FoldChange(GN5R vs. GN5V)
FDR Adjust. p-value(GN5R vs. GN5V)
Mean(GN5R)
Mean(GN5V)
SYMBOL
DEFINITION
ENTREZ_GENE_ID
ACCESSION
ONTOLOGY_COMPONENT
ONTOLOGY_PROCESS
ONTOLOGY_FUNCTION

Data table
Probe ID	FoldChange(GN5R vs. GN5V)	FDR Adjust. p-value(GN5R vs. GN5V)	Mean(GN5R)	Mean(GN5V)	SYMBOL	DEFINITION	ENTREZ_GENE_ID	ACCESSION	ONTOLOGY_COMPONENT	ONTOLOGY_PROCESS	ONTOLOGY_FUNCTION
ILMN_1360661	2.03	4.78E-08	287.1	141.2	Ankrd1	Rattus norvegicus ankyrin repeat domain 1 (cardiac muscle) (Ankrd1), mRNA.	27064	NM_013220.1	transcription factor complex [goid 5667] [evidence ISS]; nucleus [goid 5634] [evidence TAS]; cytoplasm [goid 5737] [evidence ISS]	regulation of transcription from RNA polymerase II promoter [goid 6357] [evidence ISS]; defense response [goid 6952] [evidence ISS]; regulation of transcription, DNA-dependent [goid 6355] [evidence ISS]; negative regulation of transcription [goid 16481] [evidence TAS]; signal transduction [goid 7165] [evidence ISS]	transcription cofactor activity [goid 3712] [evidence TAS]; transcription corepressor activity [goid 3714] [evidence ISS]; transcription factor activity [goid 3700] [evidence ISS]; DNA binding [goid 3677] [evidence ISS]
ILMN_1361640	2.01	0.000114171	3870.8	1924.9	Ltbp2	Rattus norvegicus latent transforming growth factor beta binding protein 2 (Ltbp2), mRNA.	59106	NM_021586.1	extracellular matrix (sensu Metazoa) [goid 5578] [evidence ISS]; extracellular space [goid 5615] [evidence ISS]	extracellular transport [goid 6858] [evidence ISS]; protein targeting [goid 6605] [evidence ISS]; protein secretion [goid 9306] [evidence ISS]; transforming growth factor beta receptor signaling pathway [goid 7179] [evidence NAS]	growth factor binding [goid 19838] [evidence IEA]
ILMN_1363231	2.00	7.80E-07	1862.9	933.1	Edn1	Rattus norvegicus endothelin 1 (Edn1), mRNA.	24323	NM_012548.1	soluble fraction [goid 5625] [evidence ISS]; extracellular space [goid 5615] [evidence ISS]	skeletal development [goid 1501] [evidence ISS]; diuresis [goid 30146] [evidence ISS]; dorsal/ventral pattern formation [goid 9953] [evidence ISS]; signal transduction [goid 7165] [evidence ISS]; respiratory gaseous exchange [goid 7585] [evidence ISS]; patterning of blood vessels [goid 1569] [evidence ISS]; fluid secretion [goid 7589] [evidence ISS]; positive regulation of cell proliferation [goid 8284] [evidence TAS]; regulation of pH [goid 6885] [evidence ISS]; cartilage development [goid 51216] [evidence ISS]; cell-cell signaling [goid 7267] [evidence ISS]; rhythmic excitation [goid 43179] [evidence ISS]; heart development [goid 7507] [evidence ISS]; positive regulation of smooth muscle contraction [goid 45987] [evidence ISS]; response to hypoxia [goid 1666] [evidence ISS]; protein kinase cascade [goid 7243] [evidence IDA]; embryonic development (sensu Mammalia) [goid 1701] [evidence ISS]; G-protein coupled receptor protein signaling pathway [goid 7186] [evidence ISS]; protein kinase C activation [goid 7205] [evidence ISS]; natriuresis [goid 30147] [evidence ISS]; glucose transport [goid 15758] [evidence ISS]	protein binding [goid 5515] [evidence ISS]; hormone activity [goid 5179] [evidence ISS]; receptor binding [goid 5102] [evidence ISS]
ILMN_1356758	1.93	2.88E-06	292.7	151.8	Cxcl13	Rattus norvegicus chemokine (C-X-C motif) ligand 13 (Cxcl13), mRNA.	498335	NM_001017496.1
ILMN_1366485	1.89	3.05E-06	1705.8	902.6	RGD1359529	Rattus norvegicus similar to chromosome 1 open reading frame 63 (RGD1359529), mRNA.	362626	NM_001014193.1
ILMN_1372919	1.88	2.87E-05	2067.0	1098.6	Cyr61	Rattus norvegicus cysteine rich protein 61 (Cyr61), mRNA.	83476	NM_031327.2	extracellular matrix (sensu Metazoa) [goid 5578] [evidence TAS]; extracellular space [goid 5615] [evidence ISS]	morphogenesis [goid 9653] [evidence ISS]; patterning of blood vessels [goid 1569] [evidence ISS]; positive regulation of angiogenesis [goid 45766] [evidence TAS]; sensory perception [goid 7600] [evidence IEA]; cell adhesion [goid 7155] [evidence IEA]; chemotaxis [goid 6935] [evidence IEA]; cell proliferation [goid 8283] [evidence ISS]; positive regulation of cell migration [goid 30335] [evidence TAS]	heparin binding [goid 8201] [evidence TAS]
ILMN_1367348	1.88	3.81E-08	551.0	293.2	LOC499196	PREDICTED: Rattus norvegicus LOC499196 (LOC499196), mRNA.	499196	XM_579933.1
ILMN_1376736	1.84	4.06E-09	1087.6	591.1	Arhgap24	Rattus norvegicus Rho GTPase activating protein 24 (Arhgap24), mRNA.	305156	NM_001012032.1
ILMN_1350146	1.84	1.29E-09	1390.0	756.6	Fbln2	PREDICTED: Rattus norvegicus fibulin 2, transcript variant 2 (Fbln2), mRNA.	282583	XM_001073317.1
ILMN_1367486	1.78	1.41E-06	3460.6	1946.7	Dusp1	Rattus norvegicus dual specificity phosphatase 1 (Dusp1), mRNA.	114856	NM_053769.2		protein amino acid dephosphorylation [goid 6470] [evidence IEA]; cell cycle [goid 7049] [evidence IEA]; intracellular signaling cascade [goid 7242] [pmid 11423551] [evidence IDA]; response to oxidative stress [goid 6979] [evidence IEA]	protein tyrosine/serine/threonine phosphatase activity [goid 8138] [evidence IEA]; phosphoprotein phosphatase activity [goid 4721] [evidence IEA]; non-membrane spanning protein tyrosine phosphatase activity [goid 4726] [evidence IEA]; protein tyrosine phosphatase activity [goid 4725] [evidence IEA]; hydrolase activity [goid 16787] [evidence IEA]; MAP kinase phosphatase activity [goid 17017] [pmid 11423551] [evidence TAS]
ILMN_1349272	1.77	6.43E-06	275.1	155.6	Npr3	Rattus norvegicus natriuretic peptide receptor 3 (Npr3), mRNA.	25339	NM_012868.1	integral to membrane [goid 16021] [evidence ISS]; extracellular space [goid 5615] [evidence ISS]	skeletal development [goid 1501] [evidence ISS]	receptor activity [goid 4872] [evidence ISS]
ILMN_1367741	1.70	1.52E-05	573.6	336.7	Smad6_predicted	PREDICTED: Rattus norvegicus MAD homolog 6 (Drosophila) (predicted) (Smad6_predicted), mRNA.	367100	XM_345947.3
ILMN_1369791	1.69	2.01E-05	809.6	479.0	RGD1565408_predicted	PREDICTED: Rattus norvegicus similar to SERTA domain containing 4 (predicted) (RGD1565408_predicted), mRNA.	360899	XM_001069683.1
ILMN_1363251	1.68	4.94E-06	388.6	230.9	RGD1561512_predicted	PREDICTED: Rattus norvegicus similar to bHLH factor Math6 (predicted) (RGD1561512_predicted), mRNA.	500200	XM_575552.2
ILMN_1353747	1.66	5.59E-09	223.3	134.2	Fst	Rattus norvegicus follistatin (Fst), mRNA.	24373	NM_012561.1	extracellular region [goid 5576] [evidence ISS]; extracellular space [goid 5615] [evidence ISS]	odontogenesis (sensu Vertebrata) [goid 42475] [evidence ISS]; pattern specification [goid 7389] [evidence ISS]; negative regulation of follicle-stimulating hormone secretion [goid 46882] [evidence ISS]; development [goid 7275] [evidence ISS]; BMP signaling pathway [goid 30509] [evidence ISS]; gametogenesis [goid 7276] [evidence ISS]; female gonad development [goid 8585] [evidence ISS]; negative regulation of cell differentiation [goid 45596] [evidence ISS]	activin inhibitor activity [goid 17106] [evidence ISS]; activin binding [goid 48185] [evidence TAS]; protein binding [goid 5515] [evidence ISS]
ILMN_1357776	1.65	0.000540149	2305.4	1399.7	Cald1	Rattus norvegicus caldesmon 1 (Cald1), mRNA.	25687	NM_013146.2	actin cap [goid 30478] [evidence ISS]; membrane fraction [goid 5624] [evidence ISS]; cytoskeleton [goid 5856] [evidence ISS]	cell motility [goid 6928] [evidence ISS]; regulation of smooth muscle contraction [goid 6940] [evidence ISS]; pregnancy [goid 7565] [evidence TAS]	calmodulin binding [goid 5516] [evidence ISS]; tropomyosin binding [goid 5523] [evidence ISS]; actin binding [goid 3779] [evidence TAS]
ILMN_1361588	1.62	3.78E-05	988.1	609.4	Slfn3	Rattus norvegicus schlafen 3 (Slfn3), mRNA.	114247	NM_053687.1
ILMN_1358820	1.62	6.07E-06	721.5	445.3	Ltbp3	PREDICTED: Rattus norvegicus latent transforming growth factor beta binding protein 3 (Ltbp3), mRNA.	83838	XM_341997.2
ILMN_1367265	1.62	0.00016553	313.1	193.8	LOC317070	PREDICTED: Rattus norvegicus similar to nidogen 2 (LOC317070), mRNA.	317070	XM_229775.4
ILMN_1367103	1.59	5.36E-05	3119.9	1958.0	Adamts1	Rattus norvegicus a disintegrin-like and metallopeptidse (reprolysin type) with thrombospondin type 1 motif, 1 (Adamts1), mRNA.	79252	NM_024400.1	cytoplasmic vesicle [goid 31410] [evidence IEA]; basement membrane [goid 5604] [evidence IEA]; extracellular matrix [goid 31012] [evidence IEA]; extracellular matrix (sensu Metazoa) [goid 5578] [evidence IEA]	integrin-mediated signaling pathway [goid 7229] [evidence IEA]; negative regulation of angiogenesis [goid 16525] [evidence IEA]; kidney development [goid 1822] [evidence IEA]; negative regulation of cell proliferation [goid 8285] [evidence IEA]; ovulation (sensu Mammalia) [goid 1542] [evidence IEA]	protein binding [goid 5515] [evidence IEA]; metalloendopeptidase activity [goid 4222] [evidence IEA]; heparin binding [goid 8201] [evidence IEA]; metal ion binding [goid 46872] [evidence IEA]; integrin binding [goid 5178] [evidence IEA]

Total number of rows: 780

Table truncated, full table size 254 Kbytes.

H5DR vs. H5DV: 1.2x and FDR<0.05 For gene expression comparisons, genes with expression values less than 100 or fold change less than 1.2 were excluded from further statistical analyses. A two-sample t-test using p-value cut-off of 0.05 with multiple test correction (Benjamini and Hochberg false discovery rate) was applied for each gene to determine if the gene were differentially expressed in the pair wise comparisons. Triplicate control and rapamycin samples from each cell line were used in these comparisons. header descriptions
Probe ID
FoldChange(H5DR vs. H5DV)
FDR Adjust. p-value(H5DR vs. H5DV)
Mean(H5DR)
Mean(H5DV)
SYMBOL
DEFINITION
ENTREZ_GENE_ID
ACCESSION
ONTOLOGY_COMPONENT
ONTOLOGY_PROCESS
ONTOLOGY_FUNCTION

Data table
Probe ID	FoldChange(H5DR vs. H5DV)	FDR Adjust. p-value(H5DR vs. H5DV)	Mean(H5DR)	Mean(H5DV)	SYMBOL	DEFINITION	ENTREZ_GENE_ID	ACCESSION	ONTOLOGY_COMPONENT	ONTOLOGY_PROCESS	ONTOLOGY_FUNCTION
ILMN_1364113	2.78	3.59E-08	1873.5	675.1	Ctgf	Rattus norvegicus connective tissue growth factor (Ctgf), mRNA.	64032	NM_022266.2	extracellular region [goid 5576] [evidence ISS]; extracellular space [goid 5615] [evidence ISS]; plasma membrane [goid 5886] [evidence ISS]; extracellular matrix (sensu Metazoa) [goid 5578] [evidence ISS]; soluble fraction [goid 5625] [evidence ISS]	response to wounding [goid 9611] [evidence ISS]; ossification [goid 1503] [evidence ISS]; cell-matrix adhesion [goid 7160] [evidence ISS]; fibroblast growth factor receptor signaling pathway [goid 8543] [evidence ISS]; epidermis development [goid 8544] [evidence ISS]; angiogenesis [goid 1525] [evidence TAS]; cell motility [goid 6928] [evidence ISS]; cartilage condensation [goid 1502] [evidence ISS]; cell adhesion [goid 7155] [evidence TAS]; intracellular signaling cascade [goid 7242] [evidence IDA]; cell differentiation [goid 30154] [evidence ISS]; cell migration [goid 16477] [evidence ISS]; integrin-mediated signaling pathway [goid 7229] [evidence ISS]	growth factor activity [goid 8083] [evidence IDA]; integrin binding [goid 5178] [evidence ISS]; insulin-like growth factor binding [goid 5520] [evidence ISS]; heparin binding [goid 8201] [evidence TAS]
ILMN_1361666	1.86	0.000146437	638.5	342.7	Mmp3	Rattus norvegicus matrix metallopeptidase 3 (Mmp3), mRNA.	171045	NM_133523.1	extracellular space [goid 5615] [evidence ISS]	collagen catabolism [goid 30574] [evidence IEA]	calcium ion binding [goid 5509] [evidence IEA]; stromelysin 1 activity [goid 4248] [evidence IEA]
ILMN_1376388	1.83	9.75E-06	212.0	116.1	Cav1	Rattus norvegicus caveolin, caveolae protein 1 (Cav1), transcript variant 2, mRNA.	25404	NM_133651.1	lipid raft [goid 45121] [evidence ISS]; caveola [goid 5901] [evidence TAS]; caveolar membrane [goid 16599] [evidence ISS]; integral to membrane of membrane fraction [goid 299] [evidence ISS]; integral to plasma membrane [goid 5887] [evidence ISS]; membrane [goid 16020] [evidence IEA]; plasma membrane [goid 5886] [evidence ISS]; integral to membrane [goid 16021] [evidence TAS]; perinuclear region [goid 48471] [evidence ISS]; endoplasmic reticulum [goid 5783] [evidence ISS]; Golgi membrane [goid 139] [evidence ISS]	cholesterol transport [goid 30301] [evidence TAS]; sequestering of lipid [goid 19915] [evidence ISS]; negative regulation of nitric oxide biosynthesis [goid 45019] [evidence ISS]; negative regulation of signal transduction [goid 9968] [evidence ISS]; cholesterol homeostasis [goid 42632] [evidence ISS]; positive regulation of vasoconstriction [goid 45907] [evidence ISS]; endocytosis [goid 6897] [evidence ISS]; negative regulation of endothelial cell proliferation [goid 1937] [evidence ISS]; triacylglycerol metabolism [goid 6641] [evidence ISS]; negative regulation of cell proliferation [goid 8285] [evidence ISS]; protein homooligomerization [goid 51260] [evidence ISS]; protein oligomerization [goid 51259] [evidence ISS]; inactivation of MAPK activity [goid 188] [evidence ISS]; negative regulation of vasodilation [goid 45908] [evidence ISS]; transcytosis [goid 45056] [evidence TAS]; regulation of fatty acid metabolism [goid 19217] [evidence ISS]	syntaxin binding [goid 19905] [evidence IMP]; structural molecule activity [goid 5198] [evidence ISS]; protein binding [goid 5515] [evidence ISS]; SNARE binding [goid 149] [evidence IMP]; cholesterol binding [goid 15485] [evidence ISS]
ILMN_1357730	1.77	4.01E-07	898.1	507.7	Npy	Rattus norvegicus neuropeptide Y (Npy), mRNA.	24604	NM_012614.1	cell [goid 5623] [evidence ISS]; extracellular space [goid 5615] [evidence ISS]	phosphoinositide-mediated signaling [goid 48015] [evidence IMP]; synaptic transmission [goid 7268] [evidence ISS]; circulation [goid 8015] [evidence ISS]; G-protein signaling, coupled to cyclic nucleotide second messenger [goid 7187] [evidence ISS]; cell proliferation [goid 8283] [evidence ISS]; digestion [goid 7586] [evidence ISS]; negative regulation of blood pressure [goid 45776] [evidence IMP]; calcium ion transport [goid 6816] [evidence ISS]; cell motility [goid 6928] [evidence ISS]; neuropeptide signaling pathway [goid 7218] [evidence IMP]; feeding behavior [goid 7631] [evidence NAS]	G-protein-coupled receptor binding [goid 1664] [evidence TAS]; neuropeptide hormone activity [goid 5184] [evidence ISS]; G-protein coupled receptor activity [goid 4930] [evidence ISS]; neuropeptide Y receptor activity [goid 4983] [evidence TAS]; calcium channel regulator activity [goid 5246] [evidence ISS]
ILMN_1357041	1.74	1.46E-06	282.5	162.0	Pcp4	Rattus norvegicus Purkinje cell protein 4 (Pcp4), mRNA.	25510	NM_013002.2		central nervous system development [goid 7417] [evidence ISS]	calcium ion binding [goid 5509] [evidence ISS]
ILMN_1371619	1.74	0.000417712	309.1	178.1	Kbtbd9_predicted	PREDICTED: Rattus norvegicus kelch repeat and BTB (POZ) domain containing 9 (predicted) (Kbtbd9_predicted), mRNA.	298867	XM_001071030.1
ILMN_1372740	1.72	1.30E-06	677.4	393.0	Col15a1	PREDICTED: Rattus norvegicus procollagen, type XV (Col15a1), mRNA.	298069	XM_001066530.1
ILMN_1350180	1.71	0.007542406	915.6	534.2	Emp1	Rattus norvegicus epithelial membrane protein 1 (Emp1), mRNA.	25314	NM_012843.2	plasma membrane [goid 5886] [evidence IPI]; integral to membrane [goid 16021] [evidence TAS]; membrane fraction [goid 5624] [evidence ISS]	cell growth [goid 16049] [evidence ISS]; cell death [goid 8219] [evidence ISS]; cell proliferation [goid 8283] [evidence ISS]; epithelial cell differentiation [goid 30855] [evidence IEP]; development [goid 7275] [evidence ISS]; epidermis development [goid 8544] [evidence ISS]
ILMN_1352307	1.66	0.000375385	407.4	245.6	Pepd	Rattus norvegicus peptidase D (Pepd), mRNA.	292808	NM_001009641.1
ILMN_1362451	1.61	0.000161951	2966.4	1838.5	Rgs2	Rattus norvegicus regulator of G-protein signaling 2 (Rgs2), mRNA.	84583	NM_053453.1	nucleus [goid 5634] [evidence ISS]	cell cycle [goid 7049] [evidence IEA]; transmembrane receptor protein tyrosine kinase signaling pathway [goid 7169] [evidence ISS]; G-protein coupled receptor protein signaling pathway [goid 7186] [evidence ISS]; negative regulation of G-protein coupled receptor protein signaling pathway [goid 45744] [evidence TAS]; regulation of G-protein coupled receptor protein signaling pathway [goid 8277] [evidence ISS]	GTPase activator activity [goid 5096] [evidence ISS]; calmodulin binding [goid 5516] [evidence ISS]
ILMN_1355544	1.59	0.000454423	820.7	515.6	LOC498276	PREDICTED: Rattus norvegicus similar to Fc gamma (IgG) receptor II (low affinity) alpha precursor - rat (LOC498276), mRNA.	498276	XM_573502.1
ILMN_1356793	1.56	1.29E-05	2514.6	1608.9	F3	Rattus norvegicus coagulation factor III (F3), mRNA.	25584	NM_013057.2	plasma membrane [goid 5886] [evidence ISS]; integral to membrane [goid 16021] [evidence ISS]	immune response [goid 6955] [evidence ISS]; blood coagulation [goid 7596] [evidence ISS]	transmembrane receptor activity [goid 4888] [evidence ISS]
ILMN_1370638	1.54	0.001104848	408.6	266.0	LOC498277	PREDICTED: Rattus norvegicus similar to Low affinity immunoglobulin gamma Fc region receptor III precursor (IgG Fc receptor III) (Fc-gamma RIII) (FcRIII) (LOC498277), mRNA.	498277	XR_007542.1
ILMN_1362987	1.52	0.00023093	564.1	371.1	Hgfac	Rattus norvegicus hepatocyte growth factor activator (Hgfac), mRNA.	58947	NM_053320.1	extracellular space [goid 5615] [evidence ISS]
ILMN_1369005	1.50	0.001721618	314.0	209.1	Egr1	Rattus norvegicus early growth response 1 (Egr1), mRNA.	24330	NM_012551.1	nucleus [goid 5634] [evidence ISS]	regulation of transcription, DNA-dependent [goid 6355] [evidence ISS]; transcription [goid 6350] [evidence IEA]; learning and/or memory [goid 7611] [evidence IEP]; positive regulation of transcription from RNA polymerase II promoter [goid 45944] [evidence IDA]	metal ion binding [goid 46872] [evidence IEA]; DNA binding [goid 3677] [evidence IEA]; transcription factor activity [goid 3700] [evidence ISS]; transcriptional activator activity [goid 16563] [evidence IDA]
ILMN_1374391	1.49	0.002493124	3865.1	2591.2	Rhoc_predicted	PREDICTED: Rattus norvegicus ras homolog gene family, member C (predicted) (Rhoc_predicted), mRNA.	295342	XM_215659.4
ILMN_1354206	1.49	0.000146437	2798.2	1879.6	Tuba1a	Rattus norvegicus tubulin, alpha 1A (Tuba1a), mRNA.	64158	NM_022298.1	microtubule [goid 5874] [evidence TAS]	microtubule-based process [goid 7017] [evidence TAS]; microtubule-based movement [goid 7018] [evidence ISS]	GTP binding [goid 5525] [evidence ISS]; structural molecule activity [goid 5198] [evidence ISS]; protein domain specific binding [goid 19904] [evidence IDA]; nucleotide binding [goid 166] [evidence IEA]; protein heterodimerization activity [goid 46982] [evidence TAS]
ILMN_1372967	1.48	0.031442731	3794.0	2561.4	Laptm4a	Rattus norvegicus lysosomal-associated protein transmembrane 4A (Laptm4a), mRNA.	298875	NM_199384.1	lysosome [goid 5764] [evidence ISS]; integral to membrane [goid 16021] [evidence ISS]; endosome [goid 5768] [evidence ISS]	xenobiotic metabolism [goid 6805] [evidence ISS]; intracellular transport [goid 46907] [evidence ISS]
ILMN_1355751	1.48	0.000767567	259.7	175.4	Zfp523_predicted	PREDICTED: Rattus norvegicus zinc finger protein 523 (predicted) (Zfp523_predicted), mRNA.	361809	XM_001068197.1
ILMN_1352782	1.47	0.038532901	844.6	572.7	Tpp1	Rattus norvegicus tripeptidyl peptidase I (Tpp1), mRNA.	83534	NM_031357.1	lysosome [goid 5764] [evidence ISS]; mitochondrion [goid 5739] [evidence ISS]; extracellular space [goid 5615] [evidence ISS]	lipid metabolism [goid 6629] [evidence ISS]	tripeptidyl-peptidase I activity [goid 19131] [evidence ISS]; serine-type endopeptidase activity [goid 4252] [evidence IEA]; peptidase activity [goid 8233] [evidence IEA]

Total number of rows: 637

Table truncated, full table size 206 Kbytes.

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GSE17662_RAW.tar	2.8 Mb	(http)(custom)	TAR
GSE17662_raw_data.txt.gz	1.7 Mb	(ftp)(http)	TXT
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