|
| Status |
Public on Sep 01, 2021 |
| Title |
Single cell RNA sequencing of healthy donor human CAR-T cells and adjacent tumor tissue from NSG mice bearing ASPC-1 tumors that are treated with CAR-T cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The goal of this study was to assess the consequences of RN7SL1 production on CAR-T cell gene expression cells within the ASCP-1 tumor microenvironment. RN7SL1 RNA-producing CAR-T cells are the relevant experimental condition, while control M5BBz CAR-T cells are also collected.
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| |
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| Overall design |
Single-cell mRNA profiles. 10X 3' v3.1 chemistry utilized.
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| |
|
| Contributor(s) |
Minn AJ, Johnson LR |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Jul 01, 2021 |
| Last update date |
Sep 03, 2021 |
| Contact name |
Lexus Johnson |
| E-mail(s) |
lexusj@mail.med.upenn.edu
|
| Phone |
3154816542
|
| Organization name |
University of Pennsylvania
|
| Department |
Radiation Oncology
|
| Lab |
Minn
|
| Street address |
421 Curie Blvd, 532
|
| City |
Philadelphia |
| State/province |
Pennsylvania |
| ZIP/Postal code |
19104 |
| Country |
USA |
| |
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| Platforms (1) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA742924 |
| SRA |
SRP326464 |
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