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Series GSE18126 Query DataSets for GSE18126
Status Public on May 05, 2010
Title Methylation status in AG- and PG-derived cells and sperm
Organism Mus musculus
Experiment type Methylation profiling by genome tiling array
Summary Genomic imprinting describes the expression of a subset of mammalian genes from one parental chromosome. The parent-of-origin specific expression of imprinted genes relies on DNA methylation of CpG-dinucleotides at differentially methylated regions (DMRs) during gametogenesis. We identified the paternally methylated DMRs at mouse chromosome 1 near the imprinted Zdbf2 gene using a methylated-DNA immunoprecipitation-on-chip (meDIP-on-chip) method applied to DNA from parthenogenetic (PG)- and androgenetic (AG)-derived cells and sperm.
 
Overall design To identify novel DMRs, genome-wide methylation analysis of three samples were performed using MeDIP and whole genome tiling array.
 
Contributor(s) Hiura H, Sugawara A, Ogawa H, John RM, Miyauchi N, Miyanari Y, Horiike T, Li Y, Yaegashi N, Sasaki H, Kono T, Arima T
Citation(s) 20385583
Submission date Sep 16, 2009
Last update date Mar 22, 2012
Contact name Hitoshi Hiura
E-mail(s) h_hiura@med.tohoku.ac.jp
Phone +81 22 717 7844
Organization name Tohoku University Graduate School of Medicine
Department Obstetrics and Gynecology
Street address 2-1 Seiryo-cho, Aoba-ku
City Sendai
ZIP/Postal code 980-8575
Country Japan
 
Platforms (25)
GPL9585 Agilent-015310 Mouse Whole Genome ChIP-on-Chip Set 244K - 1 of 25 (Probe Name version)
GPL9586 Agilent-015311 Mouse Whole Genome ChIP-on-Chip Set 244K - 2 of 25 (Probe Name version)
GPL9587 Agilent-015312 Mouse Whole Genome ChIP-on-Chip Set 244K - 3 of 25 (Probe Name version)
Samples (75)
GSM453343 Mouse androgenetic (AG)-derived cells_MeDIP-chip
GSM453344 Mouse parthenogenetic (PG)-derived cells_MeDIP-chip
GSM453345 Mouse sperm_MeDIP-chip
This SubSeries is part of SuperSeries:
GSE21662 A tripartite paternally methylated region within the Gpr1-Zdbf2 imprinted domain on mouse chromosome 1 identified by meDIP-on-chip
Relations
BioProject PRJNA129043

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE18126_RAW.tar 4.5 Gb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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