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| Status |
Public on Sep 09, 2010 |
| Title |
Williams-Beuren syndrome: typical deletions versus atypical deletions of the 7q11.23 region |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
We have performed comparative transcriptome profile from lymphoblastoid cell lines from four Williams-Beuren syndrome patients and two patients with partial deletions of the region. The goal was to find deregulated genes specifically in WBS versus atypical deletions, and to determine the biological pathways affected in WBS patients.
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| Overall design |
6 samples were hybridized twice each: once labeled with Cy5 and once labeled with Cy3 (dye-swap). Each sample was hybridized against a pool of five controls of the same gender.
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| Contributor(s) |
Antonell A, Vilardell M, Pérez-Jurado AL |
| Citation(s) |
20401492 |
| Submission date |
Sep 21, 2009 |
| Last update date |
Dec 06, 2012 |
| Contact name |
Anna Antonell |
| E-mail(s) |
antonell@clinic.ub.es
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| Organization name |
Hospital Clínic Barcelona
|
| Department |
Unitat d'Alzheimer i altres transtorns cognitius
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| Lab |
Malalties neurodegeneratives
|
| Street address |
C/Casanova, 143
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| City |
Barcelona |
| ZIP/Postal code |
08036 |
| Country |
Spain |
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| Platforms (1) |
| GPL1708 |
Agilent-012391 Whole Human Genome Oligo Microarray G4112A (Feature Number version) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA119549 |
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