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| Status |
Public on Nov 30, 2022 |
| Title |
An ancestral Wnt-Brachyury feedback loop and vertebrate-specific recruitment of mesoderm-determining target genes revealed by comparative Brachyury target screens |
| Organism |
Nematostella vectensis |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
Transcription factor brachyury plays a key role during mesoderm development in vertebrates. In this study we study study the effect of this transcription factor in diploblastic cnidarian model organism N. vectensis
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| Overall design |
Brachyury binding sites were identified with ChIP-seq and effect of brachyury binding on gene expression was studied with RNA-seq
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| Contributor(s) |
Dnyansagar R, Schwaiger M, Andrikou C, Technau U |
| Citation missing |
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| Submission date |
Aug 23, 2021 |
| Last update date |
Nov 30, 2022 |
| Contact name |
Rohit Anil Dnyansagar |
| E-mail(s) |
rohit.dnyansagar@univie.ac.at
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| Organization name |
University of Vienna
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| Department |
Department of Molecular Evolution and Development
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| Street address |
Althanstrasse 14 (UZA1) A-1090 Wien
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| City |
Vienna |
| ZIP/Postal code |
1090 |
| Country |
Austria |
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| Platforms (2) |
| GPL17090 |
Illumina HiSeq 2000 (Nematostella vectensis) |
| GPL23802 |
Illumina HiSeq 2500 (Nematostella vectensis) |
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| Samples (17)
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| Relations |
| BioProject |
PRJNA756953 |
| SRA |
SRP333687 |
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