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Series GSE18275 Query DataSets for GSE18275
Status Public on Dec 30, 2009
Title Macrophages heterogeneity in human atherosclerotic plaques
Organism Homo sapiens
Experiment type Expression profiling by array
Summary This study aims to characterize the transcriptional profile of Granulocyte-macrophage colony-stimulating factor induced macrophages (GM-MØ) and M-CSF macrophages (M-MØ) and to investigate in situ a subset of genes and their products specific to each phenotype in human atherosclerosis plaques
 
Overall design 18 RNG/MRC two-colour oligonucleotide microarrays (Le Brigand et al. 2006) were used to generate global mRNA expression profiles for GM-CSF-induced, M-CSF-induced, and peritoneal macrophages. The microarray experiments were conducted either as a common reference (peritoneal-like macrophages) design or using a direct design by hybridizing Granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced human monocyte-derived macrophage (GM-MØ) and CSF-induced human monocyte-derived macrophages(M-MØ) on the same arrays
 
Contributor(s) Brochériou I, Maouche S, Durand H, Braunersreuther V, Le Naour G, Kzhyshkowska J, Koskas F, Mach F, Cambien F, Ninio E
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Submission date Sep 25, 2009
Last update date Mar 21, 2012
Contact name Seraya Maouche
E-mail(s) seraya.maouche@upmc.fr
Fax +33140779728
URL http://genecanvas.idf.inserm.fr/news.php
Organization name INSERM U937
Department Cardiovascular Genomics
Street address 91 Bd de l'Hôpital
City Paris
State/province Paris
ZIP/Postal code 75634 Paris Cedex 13
Country France
 
Platforms (1)
GPL1946 RNG-MRC_HU25k_EVRY
Samples (18)
GSM456445 AVZ 28_MCSF_Serum
GSM456446 AVZ 30_MCSF_Serum
GSM456447 AVZ 32_MCSF_Serum
Relations
BioProject PRJNA117949

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE18275_RAW.tar 35.9 Mb (http)(custom) TAR (of GPR)
Raw data provided as supplementary file
Processed data included within Sample table

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