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| Status |
Public on Aug 07, 2022 |
| Title |
RNA-seq of homogenized lungs of APOE knock-in mice during COVID-19 II |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Here we analyze the transcriptional profiles of homogenized lungs resected from APOE2, APOE3, and APOE4 knock-in mice on day 4 post infection with SARS-CoV-2 MA10. This experiment validated a prior RNA-seq experiment revealing blunted adaptive immunity in APOE2 and APOE4 mice during COVID-19 progression.
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| |
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| Overall design |
Weighted gene co-expression network analysis and pathway analysis of RNA-sequencing data.
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| |
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| Contributor(s) |
Ostendorf BN |
| Citation(s) |
36130725 |
| Submission date |
Sep 16, 2021 |
| Last update date |
Oct 20, 2022 |
| Contact name |
Benjamin N Ostendorf |
| Organization name |
Charité University Medicine
|
| Street address |
Augustenburger Platz 1
|
| City |
Berlin |
| ZIP/Postal code |
13353 |
| Country |
Germany |
| |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (24)
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| This SubSeries is part of SuperSeries: |
| GSE184289 |
RNA-seq of homogenized lungs of APOE knock-in mice during COVID-19 |
|
| Relations |
| BioProject |
PRJNA763901 |
| SRA |
SRP337449 |
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