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| Status |
Public on Jan 09, 2010 |
| Title |
Identification of the Early VIP Transriptome and its Associated Interactome in Resting Murine CD4 T Cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Identification of the Early Vasoactive Intestinal Peptide (VIP) Transriptome and its Associated Interactome in Resting Murine CD4 T Cells
In an attempt to understand the biological role of this neuropeptide in the immune system, we choose CD4 T cells as a cellular system for identifying a VIP-induced transcriptome.
Murine CD4 T cells were isolated and used to identify changes in gene expression in the absence of PMA/ionomycin (resting) with and without 10-7 M VIP.
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| Overall design |
Balanced-block design, 6 biological replicates. Naïve mouse CD4 T spleenocytes with VIP ligand (sample) vs. naïve mouse CD4 T spleenocytes without VIP ligand (control), dye-swaps.
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| Contributor(s) |
Dorsam ST, Vomhof-Dekrey E, Hermann R, Haring J, van der Steen T, Wilkerson E, Boskovic G, Denvir J, Dementieva Y, Primerano D, Dorsam GP |
| Citation(s) |
20117839 |
| Submission date |
Oct 12, 2009 |
| Last update date |
May 10, 2018 |
| Contact name |
Yulia Dementieva |
| E-mail(s) |
dementieva@marshall.edu
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| Phone |
(304)6966643
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| Organization name |
Marshall University
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| Department |
Mathematics
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| Street address |
One John Marshall Drive
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| City |
Huntington |
| State/province |
WV |
| ZIP/Postal code |
25755 |
| Country |
USA |
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| Platforms (1) |
| GPL4134 |
Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Feature Number version) |
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| Samples (6)
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| GSM461408 |
spleenocytes with VIP vs. spleenocytes without VIP, Resting, Replicate 1 |
| GSM461409 |
spleenocytes with VIP vs. spleenocytes without VIP, Resting, Replicate 2 |
| GSM461410 |
spleenocytes with VIP vs. spleenocytes without VIP, Resting, Replicate 3 |
| GSM461411 |
spleenocytes with VIP vs. spleenocytes without VIP, Resting, Replicate 4 |
| GSM461412 |
spleenocytes with VIP vs. spleenocytes without VIP, Resting, Replicate 5 |
| GSM461413 |
spleenocytes with VIP vs. spleenocytes without VIP, Resting, Replicate 6 |
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| This SubSeries is part of SuperSeries: |
| GSE18526 |
Identification of the Early VIP Transriptome and its Associated Interactome in Resting and Activated Murine CD4 T Cells |
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| Relations |
| BioProject |
PRJNA123713 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE18524_RAW.tar |
100.1 Mb |
(http)(custom) |
TAR (of TXT) |
| Processed data included within Sample table |
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