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Series GSE18528 Query DataSets for GSE18528
Status Public on Oct 01, 2010
Title Comparative analysis of ependymal cells from the lateral ventricular wall and the spinal cord of adult mice
Organism Mus musculus
Experiment type Expression profiling by array
Summary In contrast to ependymal cells in the lateral ventricle wall (LVW), spinal cord (SC) ependymal cells possess certain neural stem cell characteristics. Isolated CD133+/CD24+/CD45-/CD34- ependymal cells from the SC displayed in vitro self renewal and differentiation capacity, whereas those from the LVW did not.
The molecular basis of this difference is unknown. In this study, antibodies against multiple surface markers were applied to isolate SC and LVW ependymal cells which allowed a direct comparison of their in vitro behavior and gene expression profile.
 
Overall design cRNA samples of three independent biological replicates of CD133+/CD24+/CD45-/CD34- LVW ependymal cells, CD133+/CD24+/CD45-/CD34- SC ependymal cells, CD133+/CD24-/CD45-/CD34- radial glial cells, and SC ependymal cell-derived NSPs were hybridized onto Illumina MouseWG-6 v1.1 gene expression arrays
 
Contributor(s) Pfenninger CV, Nuber UA
Citation(s) 21046556
Submission date Oct 13, 2009
Last update date Jan 18, 2013
Contact name Ulrike A. Nuber
Organization name Lund University
Street address Klinikgatan 26
City Lund
ZIP/Postal code SE-22184
Country Sweden
 
Platforms (1)
GPL6105 Illumina mouse-6 v1.1 expression beadchip
Samples (12)
GSM461505 Lateral ventricle wall ependymal cells rep 1
GSM461506 Lateral ventricle wall ependymal cells rep 2
GSM461507 Lateral ventricle wall ependymal cells rep 3
Relations
BioProject PRJNA120203

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE18528_RAW.tar 5.2 Mb (http)(custom) TAR
GSE18528_raw_data.txt.gz 4.1 Mb (ftp)(http) TXT
Processed data included within Sample table

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