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Series GSE185952 Query DataSets for GSE185952
Status Public on Oct 15, 2021
Title For lncRNA, circRNA and mRNA sequencing of thyroid-associated ophthalmopathy patients and normal people
Organism Homo sapiens
Experiment type Expression profiling by array
Non-coding RNA profiling by array
Summary We identified the differentially expressed mRNAs and lncRNAs/circRNAs of the case group and the control group through high-throughput sequencing technology, performed a functional enrichment analysis of the differentially expressed genes, and used protein-protein interaction (PPI) analysis to identify the hub genes.
A novel ceRNA network was successfully established, and the network components may serve as promising diagnostic biomarkers or therapeutic targets for thyroid-associated ophthalmopathy in the future.
Overall design Orbital adipose/connective tissue was obtained from 3 thyroid-associated ophthalmopathy patients with no history of thyroid disease, inflammatory disease, autoimmune disease, or orbital disease. All the thyroid-associated ophthalmopathy patients underwent orbital decompression for proptosis correction, and control subjects underwent cosmetic upper and lower blepharoplasty. The 3 control groups were obtained from the tissue remains of healthy people after plastic surgery.
Contributor(s) Yue Z, Tong F
Citation(s) 34976024
Submission date Oct 14, 2021
Last update date Jan 10, 2022
Contact name Zifan Yue
Phone 15821673019
Organization name Shanghai Changzheng Hospital
Department Ophthalmology
Street address No. 415 Fengyang Road, Hangpu District
City Shanghai
ZIP/Postal code 200001
Country China
Platforms (1)
GPL30862 Agilent-086360 Shbio Human (4*180K) array
Samples (6)
GSM5627753 Orbital adipose/connective tissue_excised_rep1
GSM5627754 Orbital adipose/connective tissue_excised_rep2
GSM5627755 Orbital adipose/connective tissue_excised_rep3
BioProject PRJNA771460

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE185952_Normalized_Data.txt.gz 16.8 Mb (ftp)(http) TXT
GSE185952_RAW.tar 147.3 Mb (http)(custom) TAR (of TXT)
Raw data provided as supplementary file
Processed data included within Sample table
Processed data are available on Series record

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