 |
 |
GEO help: Mouse over screen elements for information. |
|
| Status |
Public on Mar 01, 2010 |
| Title |
Comparison of gene expression in mouse placentas with different combination of MT1-MMP and MT2-MMP alleles |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
MT1-MMP and MT2-MMP double deficiency in mice leads to development of a placental defect resulting in embryonic death after E10.5. The protein substrate for these two proteases in placenta is unknown, which poses an obstacle in uncovering of molecular mechanism behind the observed placental defect. In search for a potential substrate for these two proteases in placenta we have employed whole genome microarray expression profiling as a discovery platform to identify genes, expression of which might be affected by double MMP deficiency.
|
| |
|
| Overall design |
Fetal parts of mouse placentas were isolated from E10.5 placentas of different genotypes for MT1- and MT2-MMP.
|
| |
|
| Contributor(s) |
Szabova L |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Oct 16, 2009 |
| Last update date |
May 10, 2018 |
| Contact name |
Kenn Holmbeck |
| Organization name |
NIDCR
|
| Street address |
30 Convent Drive
|
| City |
Bethesda |
| State/province |
MD |
| ZIP/Postal code |
20892-4380 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL4134 |
Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Feature Number version) |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA121429 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE18604_GeneSpring_results5-16-09.xls.gz |
825.0 Kb |
(ftp)(http) |
XLS |
| GSE18604_RAW.tar |
114.6 Mb |
(http)(custom) |
TAR (of TXT) |
| Processed data included within Sample table |
| Processed data are available on Series record |
|
|
|
|
 |
Less...
More...