|
| Status |
Public on Nov 09, 2010 |
| Title |
Expression analysis in yeast model of Huntington's disease (HD) |
| Organism |
Saccharomyces cerevisiae |
| Experiment type |
Expression profiling by array
|
| Summary |
Expressing a mutant fragment of huntingtin (Htt) in yeast produces several HD-relevant phenotypes. We used microarrays to study global change in expression induced by this mutant htt fragment.
Expression was also analysed in three suppressor deletion strains expressing a toxic mutant htt fragment: bna4Δ, mbf1Δ, and ume1Δ.
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| |
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| Overall design |
Yeast samples expressing either a wild-type or mutant htt fragment (Htt25Q or Htt103Q, respectively), and suppressor deletion strains expressing Htt103Q: bna4Δ, mbf1Δ, and ume1Δ.
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| |
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| Contributor(s) |
Tauber E, Giorgini F |
| Citation(s) |
21044956 |
| Submission date |
Oct 20, 2009 |
| Last update date |
Jul 01, 2016 |
| Contact name |
Eran Tauber |
| Organization name |
University of Leicester
|
| Department |
Genetics
|
| Street address |
University Road
|
| City |
Leicester |
| ZIP/Postal code |
LE1 7RH |
| Country |
United Kingdom |
| |
|
| Platforms (1) |
| GPL90 |
[YG_S98] Affymetrix Yeast Genome S98 Array |
|
| Samples (15)
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|
| Relations |
| BioProject |
PRJNA121577 |
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