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Status |
Public on Sep 27, 2010 |
Title |
Gene expression profile of bone marrow with post-irradiation radioprotector |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
To elucidate the mechanism of the in vivo radioprotection activity of Zn-containing heat-treated Saccharomyces cerevisiae yeast (Zn-yeast), expression changes in bone marrow after whole body irradiation (WBI) with concomitant treatment of Zn-yeast were analyzed using microarray technology.
Keywords: mouse, bone marrow, Zn-containing heat-treated yeast administration, gamma-irradiation
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Overall design |
Zn-yeast suspension was administered i.p. into C3H mice immediately after 7.5 Gy WBI. Bone marrow from irradiated mice was extracted at 6 hours after irradiation and analyzed by microarray containing of 44,000 probes.
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Contributor(s) |
Imadome K, Iwakawa M |
Citation(s) |
20921820 |
Submission date |
Oct 25, 2009 |
Last update date |
May 10, 2018 |
Contact name |
Kaori Imadome |
Organization name |
National institute of radiological sciences
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Department |
Research Center of Charged Particle Therapy
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Lab |
RadGenomics Project
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Street address |
Anagawa 4-9-1
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City |
Chiba |
State/province |
Chiba |
ZIP/Postal code |
2658333 |
Country |
Japan |
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Platforms (1) |
GPL4134 |
Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Feature Number version) |
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Samples (8)
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GSM382144 |
Bone marrow_non-irradiated_methylcellulose_6hr (Cy5) vs. Bone marrow_irradiated_Zn-yeast_6hr (Cy3) |
GSM382145 |
Bone marrow_irradiated_Zn-yeast_6hr (Cy5) vs. Bone marrow_non-irradiated_methylcellulose_6hr (Cy3) |
GSM382146 |
Bone marrow_non-irradiated_methylcellulose_6hr (Cy5) vs. Bone marrow_irradiated_methylcellulose_6hr (Cy3) |
GSM382147 |
Bone marrow_irradiated_methylcellulose_6hr (Cy5) vs. Bone marrow_non-irradiated_methylcellulose_6hr (Cy3) |
GSM382148 |
Bone marrow_non-irradiated_methylcellulose_6hr (Cy5) vs. Bone marrow_non-irradiated_Zn-yeast_6hr (Cy3) |
GSM382149 |
Bone marrow_non-irradiated_Zn-yeast_6hr (Cy5) vs. Bone marrow_non-irradiated_methylcellulose_6hr (Cy3) |
GSM382150 |
Bone marrow_irradiated_methylcellulose_6hr (Cy5) vs. Bone marrow_irradiated_Zn-yeast_6hr (Cy3) |
GSM382151 |
Bone marrow_irradiated_Zn-yeast_6hr (Cy5) vs. Bone marrow_irradiated_methylcellulose_6hr (Cy3) |
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Relations |
BioProject |
PRJNA121629 |