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| Status |
Public on Jun 01, 2022 |
| Title |
Mmp-13 deletion in cells of the mesenchymal lineage increases bone mass, decreases endocortical osteoclast number and attenuates the cortical bone loss caused by estrogen deficiency in mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
We generated mice with conditional Mmp-13 deletion in Prrx1 expressing cells (Mmp-13dPrrx1) and compared the effect of estrogen deficiency on their bone phenotype to that of control littermates (Mmp-13f/f)
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| |
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| Overall design |
We compare transcriptome of calvaria cells between Mmp13 knock out mice with wildtype
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| |
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| Contributor(s) |
Nookaew I, Ponte F, Almeida M |
| Citation(s) |
35715555 |
| Submission date |
Dec 19, 2021 |
| Last update date |
Jun 30, 2022 |
| Contact name |
Intawat Nookaew |
| E-mail(s) |
inookaew@uams.edu
|
| Organization name |
University of Arkansas for Medical Sciences
|
| Department |
Department of Biomedical Informatics
|
| Street address |
4301 W Markham St
|
| City |
Little Rock |
| ZIP/Postal code |
72205 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL6885 |
Illumina MouseRef-8 v2.0 expression beadchip |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA790615 |
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