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| Status |
Public on May 19, 2022 |
| Title |
NIMA Related Kinase 7 reduction mediates acetaminophen-induced acute liver injury: role of impaired cell cycle regulation |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Explored and demonstrated a new function of NEK7 in the liver against APAP-induced acute liver injury probably by dysregulating cyclins and disturbing cell cycle progression.
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for liver tissue from NEK7 whole body knockout mice with tamoxifen inducibility (iKO_1, iKO_2, iKO_3) and wild type mice (Ctrl1, Ctrl2, Ctrl3).
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| Contributor(s) |
Sun Z, Jia Z |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
May 16, 2022 |
| Last update date |
May 19, 2022 |
| Contact name |
Zhenzhen Sun |
| E-mail(s) |
sunzz2018@njmu.edu.cn
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| Organization name |
Children’s Hospital of Nanjing Medical University
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| Street address |
Guangzhou Road#72
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| City |
Nanjing |
| ZIP/Postal code |
210008 |
| Country |
China |
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| Platforms (1) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA838624 |
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