|
Status |
Public on May 19, 2022 |
Title |
NIMA Related Kinase 7 reduction mediates acetaminophen-induced acute liver injury: role of impaired cell cycle regulation |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
|
Summary |
Explored and demonstrated a new function of NEK7 in the liver against APAP-induced acute liver injury probably by dysregulating cyclins and disturbing cell cycle progression.
|
|
|
Overall design |
Comparative gene expression profiling analysis of RNA-seq data for liver tissue from NEK7 whole body knockout mice with tamoxifen inducibility (iKO_1, iKO_2, iKO_3) and wild type mice (Ctrl1, Ctrl2, Ctrl3).
|
|
|
Contributor(s) |
Sun Z, Jia Z |
Citation missing |
Has this study been published? Please login to update or notify GEO. |
Submission date |
May 16, 2022 |
Last update date |
May 19, 2022 |
Contact name |
Zhenzhen Sun |
E-mail(s) |
sunzz2018@njmu.edu.cn
|
Organization name |
Children’s Hospital of Nanjing Medical University
|
Street address |
Guangzhou Road#72
|
City |
Nanjing |
ZIP/Postal code |
210008 |
Country |
China |
|
|
Platforms (1) |
|
Samples (6)
|
|
Relations |
BioProject |
PRJNA838624 |