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GEO help: Mouse over screen elements for information. |
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| Status |
Public on May 22, 2022 |
| Title |
Immune system modulation by the adjuvants Poly (I:C) and Montanide ISA 720 |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
We investigated the immune phenotypes induced by Poly (I:C) and Montanide ISA 720 in the context of mice immunization with a recombinant protein based on the Plasmodium vivax circumsporozoite protein sequence.
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| Overall design |
We performed RNA-Seq from lymphocyte populations (B, T CD4+ and T CD8+) isolated 14 days after the last immunization.
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| Contributor(s) |
Marques RF, De Melo FM, Gimenez AM |
| Citation(s) |
35844531 |
| Submission date |
May 17, 2022 |
| Last update date |
Jul 20, 2022 |
| Contact name |
Filipe Menegatti de Melo |
| E-mail(s) |
fizao37@gmail.com
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| Phone |
+55 11 94280 7342
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| Organization name |
University of Sao Paulo
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| Department |
Microbiology
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| Lab |
Laboratory of Applied Research in Mycobacteria (LAPAM)
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| Street address |
Avenida Professor Lineu Prestes, 1374
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| City |
Sao Paulo |
| State/province |
Sao Paulo |
| ZIP/Postal code |
05008-000 |
| Country |
Brazil |
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| Platforms (1) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
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| Samples (15)
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| GSM6164870 |
B lymphocyte, naive mice (n=6) |
| GSM6164871 |
B lymphocyte, Montanide-injected mice (n=6), 14 days after last immunization |
| GSM6164872 |
B lymphocyte, Montanide plus CSP-injected mice (n=6), 14 days after last immunization |
| GSM6164873 |
B lymphocyte, poly (I:C)-injected mice (n=6), 14 days after last immunization |
| GSM6164874 |
B lymphocyte, poly (I:C) plus CSP-injected mice (n=6), 14 days after last immunization |
| GSM6164875 |
CD4+ T cell, naive mice (n=6) |
| GSM6164876 |
CD4+ T cell, Montanide-injected mice (n=6), 14 days after last immunization |
| GSM6164877 |
CD4+ T cell, Montanide plus CSP-injected mice (n=6), 14 days after last immunization |
| GSM6164878 |
CD4+ T cell, poly (I:C)-injected mice (n=6), 14 days after last immunization |
| GSM6164879 |
CD4+ T cell, poly (I:C) plus CSP-injected mice (n=6), 14 days after last immunization |
| GSM6164880 |
CD8+ T cell, naive mice (n=6) |
| GSM6164881 |
CD8+ T cell, Montanide-injected mice (n=6), 14 days after last immunization |
| GSM6164882 |
CD8+ T cell, Montanide plus CSP-injected mice (n=6), 14 days after last immunization |
| GSM6164883 |
CD8+ T cell, poly (I:C)-injected mice (n=6), 14 days after last immunization |
| GSM6164884 |
CD8+ T cell, poly (I:C) plus CSP-injected mice (n=6), 14 days after last immunization |
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| Relations |
| BioProject |
PRJNA839078 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE203218_Bcell_all_samples_raw_reads.txt.gz |
375.7 Kb |
(ftp)(http) |
TXT |
| GSE203218_CD4_all_samples_raw_reads.txt.gz |
375.8 Kb |
(ftp)(http) |
TXT |
| GSE203218_CD8_all_samples_raw_reads.txt.gz |
371.3 Kb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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