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Series GSE203239 Query DataSets for GSE203239
Status Public on May 21, 2022
Title HDAC6 deacetylates IDH1 to regulate the homeostasis of hematopoietic stem/progenitor cells
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary In order to further explore the mechanism by which increased 5hmC inhibits expansion of LSK cells from Hdac6-/- murine primary BM cells, we performed RNA sequencing (RNA-seq) analysis using LSK cells isolated from Hdac6-/- and WT mice.
 
Overall design Comparative gene expression profiling analysis of RNA-seq data in bone marrow hematopoietic stem/progenitor cells (LSK) of wild-type and HDAC6-deficient mice
 
Contributor(s) Liu Y, Yang J, Yin H
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Submission date May 18, 2022
Last update date May 21, 2022
Contact name hanxiao Yin
E-mail(s) yinhx@mail.nankai.edu.cn
Organization name nankai university
Street address Weijin road 94
City Tianjin
ZIP/Postal code 300000
Country China
 
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (4)
GSM6165151 Lin-Sca-1hic-kit+, control 1
GSM6165152 Lin-Sca-1hic-kit+, control 2
GSM6165153 Lin-Sca-1hic-kit+, HDAC6 knockout 1
Relations
BioProject PRJNA839243

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE203239_read_count_clean_matrix.txt.gz 75.5 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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