|
| Status |
Public on Apr 16, 2010 |
| Title |
Expression data from Transgenic mice skin expressing deltaNp63alpha |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
We developed a Tet-inducible system to express deltaNp63alpha isoform under the control of keratin 5 promoter. Transgenic mice, which were Bigenic (BG) developed a severe skin phenotype with abnormal keratinocyte differentiation and defects in hair follicle development and cycling. Skin samples from transgenic animals and wild type animals were analyzed for global transcriptome changes.
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| |
|
| Overall design |
We used microarrays to performing transcriptional profiling of deltaNp63alpha transgenic and control dorsal skin at P16.
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| |
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| Contributor(s) |
Romano R, Smalley K, Liu S, Sinha S |
| Citation(s) |
20335364 |
| Submission date |
Feb 24, 2010 |
| Last update date |
Feb 11, 2019 |
| Contact name |
SATRAJIT SINHA |
| E-mail(s) |
SSINHA2@BUFFALO.EDU
|
| Organization name |
SUNY AT BUFFALO
|
| Street address |
701 ELLICOTT STREET
|
| City |
BUFFALO |
| ZIP/Postal code |
14203 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
|
| Samples (4)
|
| GSM515362 |
dorsal skin of wild type animal, biological rep1 |
| GSM515363 |
dorsal skin of wild type animal, biological rep2 |
| GSM515364 |
dorsal skin of bitransgenic animal, biological rep1 |
| GSM515365 |
dorsal skin of bitransgenic animal, biological rep2 |
|
| Relations |
| BioProject |
PRJNA125235 |
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