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Status |
Public on Mar 17, 2023 |
Title |
High-throughput Functional Analysis of Autism Genes in Zebrafish Identifies Convergence in Dopaminergic and Neuroimmune Pathways |
Organism |
Danio rerio |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
Investigation of convergence and divergence of different Autism Risk genes at the molecular level, in the brain of zebrafish ASD mutants at 6 days-post-fertilizitation (dpf)
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Overall design |
Comparative gene expression profiling analysis of bulk RNA-seq data of the high-confidence Autism Risk Genes: scn1lab and dyrk1a.
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Web link |
https://www.cell.com/cell-reports/fulltext/S2211-1247(23)00254-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2211124723002541%3Fshowall%3Dtrue
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Contributor(s) |
Weinschutz Mendes H, Neelakantan U, Liu Y, Fitzpatrick SE, Chen T, Wu W, Pruitt A, Jin DS, Jamadagni P, Carlson M, Lacadie CM, Enriquez KD, Li N, Zhao D, Ijaz S, Sakai C, Szi C, Rooney B, Ghosh M, Nwabudike I, Gorodezsky A, Chowdhury S, Zaheer M, McLaughlin S, Fernandez JM, Wu J, Eilbott JA, Vander Wyk B, Rihel J, Papademetris X, Wang Z, Hoffman EJ |
Citation(s) |
36933215 |
Submission date |
Jun 06, 2022 |
Last update date |
Jun 19, 2023 |
Contact name |
Hellen Weinschutz Mendes |
E-mail(s) |
hellen.chrisw@gmail.com
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Organization name |
Yale University
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Department |
Neuroscience
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Lab |
Hoffman Lab
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Street address |
333 Cedar Street
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City |
New Haven |
State/province |
Connecticut |
ZIP/Postal code |
06510 |
Country |
USA |
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Platforms (1) |
GPL24995 |
Illumina NovaSeq 6000 (Danio rerio) |
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Samples (19)
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Relations |
BioProject |
PRJNA846486 |
Supplementary file |
Size |
Download |
File type/resource |
GSE205578_RAW.tar |
2.8 Mb |
(http)(custom) |
TAR (of CSV) |
SRA Run Selector |
Raw data are available in SRA |
Processed data provided as supplementary file |
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