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| Status |
Public on Mar 16, 2012 |
| Title |
Mediators in Crohn’s disease influence the gene expression profiles of mesenchymal progenitor cells differentiated into the osteoblastic lineage. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Crohn’s disease (CD) is associated with a higher prevalence of osteoporosis, a complication that is increasingly recognised as a significant cause of morbidity. Its pathogenesis is still controversial, but activity of CD is thought to be one contributing factor.
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| Overall design |
Two-Color DRLL-IS-Design [Landgrebe et.al 2004: Efficient two-sample designs for microarray experiments with biological replications. In Silico Biology 4] including 12 Arrays, osteoporosis samples from 4 mc patients, control samples from 3 mc patients without osteoporosis
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| Contributor(s) |
Blaschke M, Cortis J, Baums MH, Köpp R, Raddatz D, Schuetze N, Miosge N, Salinas-Riester G, Siggelkow H |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Mar 18, 2010 |
| Last update date |
Feb 22, 2018 |
| Contact name |
Gabriela Salinas |
| E-mail(s) |
Gabriela.Salinas-Riester@medizin.uni-goettingen.de
|
| Organization name |
Universitaetsmedizin Goettingen
|
| Department |
Department of Human Genetics
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| Lab |
NGS Integrative Genomics
|
| Street address |
Justus-von-Liebig-Weg 11
|
| City |
Goettingen |
| State/province |
Lower-Saxony |
| ZIP/Postal code |
37077 |
| Country |
Germany |
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| Platforms (1) |
| GPL4133 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA124421 |
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