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| Status |
Public on Sep 19, 2022 |
| Title |
A microbiome-dependent gut–brain pathway regulates motivation for exercise |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Single nucleus RNA sequencing of mouse striatum at steady state and after exercise in mice treated and untreated with broad spectrum antibiotics.
|
| |
|
| Overall design |
Nuclei were isolated and FACS sorted based on DAPI from mouse striatum at the given conditions and subsequently used in 10X Genomics pipeline.
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| |
|
| Contributor(s) |
Dohnalova L, Lundgren P, Thaiss C |
| Citation(s) |
36517598 |
| Submission date |
Aug 10, 2022 |
| Last update date |
Dec 19, 2022 |
| Contact name |
Patrick Lundgren |
| E-mail(s) |
r.patricklundgren@gmail.com
|
| Organization name |
University of Pennsylvania
|
| Street address |
302 Johnson Pavilion, 3610 Hamilton Walk
|
| City |
Philadelphia |
| State/province |
PA |
| ZIP/Postal code |
19104 |
| Country |
USA |
| |
|
| Platforms (1) |
|
| Samples (8)
|
| GSM6440122 |
SnRNAseq of striatum from mice treated with broad spectrum antibiotics without exercise replicate 1 |
| GSM6440123 |
SnRNAseq of striatum from mice treated with broad spectrum antibiotics without exercise replicate 2 |
| GSM6440125 |
SnRNAseq of striatum from SPF mice without exercise replicate 1 |
| GSM6440126 |
SnRNAseq of striatum from SPF mice without exercise replicate 2 |
| GSM6440127 |
SnRNAseq of striatum from mice treated with broad spectrum antibiotics post exercise replicate 1 |
| GSM6440128 |
SnRNAseq of striatum from mice treated with broad spectrum antibiotics post exercise replicate 2 |
| GSM6440129 |
SnRNAseq of striatum from SPF mice post exercise replicate 1 |
| GSM6440131 |
SnRNAseq of striatum from SPF mice post exercise replicate 2 |
|
| Relations |
| BioProject |
PRJNA868302 |
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