|
| Status |
Public on Sep 13, 2010 |
| Title |
Foxo1/3-deficient Treg cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Identification of Foxos target genes in Treg cells. Foxo1and Foxo3 are transcription factors of Foxo family. CD4+Foxp3+ Treg cells isolated from wild-type and Foxo1/3-deficient mice were analyzed by global gene expression profiling. Results indicate Foxos regulate expression of a subset of Treg cell signature genes and genes in control of T cell homeostasis, signaling and metabolism.
|
| |
|
| Overall design |
2 sets wild-type and Foxo1/3-deficient CD4+Foxp3+ Treg cells
|
| |
|
| Contributor(s) |
Li MO, Ouyang W |
| Citation(s) |
20467422 |
| Submission date |
May 05, 2010 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Weiming Ouyang |
| E-mail(s) |
ouyangw1@mskcc.org
|
| Organization name |
MSKCC
|
| Street address |
415 E68ST
|
| City |
New York |
| State/province |
NY |
| ZIP/Postal code |
10021 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
|
| Samples (4)
|
|
| Relations |
| BioProject |
PRJNA125833 |
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