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| Status |
Public on Aug 15, 2010 |
| Title |
Multiple levels of gene regulation mediate differentiation of the intracellular pathogen Leishmania |
| Platform organism |
Leishmania infantum JPCM5 |
| Sample organism |
Leishmania donovani |
| Experiment type |
Expression profiling by array
|
| Summary |
Whole genome high density tiliing array of eight timepoints from the promastitgote to amastigote differentiation process.
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| Overall design |
RNA from two independent biological replicates from eight points in the promastigote to amastigote differentiation process were hybridized to Nimblegen arrays (Madison,WI USA) that contained 10 probes per open reading frame and 3 probes per structural RNA spotted three times per array. The microarray probes were designed to Leishmania infantum strain JCPM5 and the sample RNA was obtained from Leishmania donovani strain S1. The two species are thought to be nearly identical at the nucleotide level, however whole-genome sequence was not available from L. donovani.
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| Contributor(s) |
Lahav T, Sivam D, Volpin H, Anderson-Green A, Myler PJ, Zilberstein D |
| Citation(s) |
20952481 |
| Submission date |
May 20, 2010 |
| Last update date |
Jul 12, 2012 |
| Contact name |
Dhileep Sivam |
| Organization name |
Seattle Biomedical Research Institute
|
| Department |
Bioinformatics Core
|
| Lab |
Myler Lab
|
| Street address |
307 Westlake Ave N
|
| City |
Seattle |
| State/province |
WA |
| ZIP/Postal code |
98109 |
| Country |
USA |
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| Platforms (1) |
| GPL10446 |
NimbleGen Leishmania infantum JPCM5 8k Expression Array |
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| Samples (16)
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| Relations |
| BioProject |
PRJNA126877 |
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