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| Status |
Public on Mar 31, 2011 |
| Title |
Expression data of MCF-7 cells treated with gamma tocotrienol (g-T3) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Gamma tocotrienol induces apoptosis in breast cancer cells however, the molecular mechanisms are not completely understood.
We used microarrays to detail the global programme of gene expression underlying the effects of gamma tocotrienols on MCF-7 cells and identified distinct classes of up-regulated genes during this process.
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| Overall design |
MCF-7 cells were grown in DMEM medium with 5% FBS. The cells were treated with vehicle control (DMSO) or 40 uM of gamma tocotrienol for 24 h for RNA extraction and hybridization on Affymetrix microarrays. Four independent experiments were performed.
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| Contributor(s) |
Patacsil D, Tran A, Cho Y, Suy S, Saenz F, Malyukova I, Ressom H, Clarke R, Kumar D |
| Citation(s) |
21429729 |
| Submission date |
May 21, 2010 |
| Last update date |
Dec 06, 2018 |
| Contact name |
Habtom Ressom |
| Organization name |
Georgetown University
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| Street address |
4000 Reservoir Rd.
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| City |
Washington |
| State/province |
DC |
| ZIP/Postal code |
DC |
| Country |
USA |
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| Platforms (1) |
| GPL571 |
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array |
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| Samples (8)
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| GSM545861 |
MCF-7 cells-control, biological rep 1 |
| GSM545862 |
MCF-7 cells-control, biological rep 2 |
| GSM545863 |
MCF-7 cells-control, biological rep 3 |
| GSM545864 |
MCF-7 cells-control, biological rep 4 |
| GSM545865 |
MCF-7 cells-40mM g-T3, biological rep 1 |
| GSM545866 |
MCF-7 cells-40mM g-T3, biological rep 2 |
| GSM545867 |
MCF-7 cells-40mM g-T3, biological rep 3 |
| GSM545868 |
MCF-7 cells-40mM g-T3, biological rep 4 |
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| Relations |
| BioProject |
PRJNA127235 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE21946_RAW.tar |
15.9 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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