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Series GSE2250 Query DataSets for GSE2250
Status Public on Sep 11, 2009
Title Effects of irradiation on mouse lung
Organism Mus musculus
Experiment type Expression profiling by array
Summary Total lung RNA from 3 mouse strains after 18Gy thoracic irradiation.
Thoracic cavity radiotherapy is limited by the development of alveolitis and fibrosis in susceptible patients. To define the response to 18 Gy pulmonary irradiation in mice, at the expression level, and to identify pathways which may influence the alveolitis and fibrosis phenotypes expression profiling was completed. Male mice of three strains, A/J (late alveolitis response), C3H/HeJ (C3H, early alveolitis response) and C57BL/6J (B6, fibrosis response) were exposed to thoracic radiation, euthanised when moribund and lung tissue gene expression was assessed with microarrays.
 
Overall design treated vs. control in 3 strains
 
Contributor(s) Haston CK
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Feb 07, 2005
Last update date Feb 11, 2019
Contact name Christina Kathleen Haston
E-mail(s) christina.haston@mcgill.ca
Phone 514-398-3864 089714
Organization name McGill University
Department Medicine
Street address 3626 St. Urbain
City Montreal
State/province QC
ZIP/Postal code H2X 2P2
Country Canada
 
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (18)
GSM488185 AJ control 1
GSM488186 AJ control 2
GSM488187 AJ control 3
Relations
BioProject PRJNA91351

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE2250_RAW.tar 103.7 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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