|
| Status |
Public on Jul 07, 2010 |
| Title |
Genome-wide analysis of gene expression in EMT cells induced by overexpression of PDGF-D compared with PC3 control cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Analysis of EMTrelated gene expression levels. The hypothesis tested in the present study was that expression of mesenchymal markers was increased and expression of epithelial markers was downregulated concomitant with increased expression of stem -like cell markers in EMT cells compared with control cells. Results demostrated that overexpression of PDGF-D induced genome-wide gene expression changes which were consistent with EMT phenotype and stem cell signatures.
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| |
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| Overall design |
Total RNA isolated from stable PC3 Neo and PC3 PDGF-D cells.
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| |
|
| Contributor(s) |
Sarkar FH |
| Citation(s) |
20805998 |
| Submission date |
Jul 06, 2010 |
| Last update date |
Feb 18, 2019 |
| Contact name |
Fazlul H. Sarkar |
| E-mail(s) |
fsarkar@med.wayne.edu
|
| Phone |
313-576-8327
|
| Organization name |
Wayne State University School of Medicine
|
| Department |
Pathology
|
| Street address |
4100 John R
|
| City |
Detroit |
| State/province |
MI |
| ZIP/Postal code |
48201 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6884 |
Illumina HumanWG-6 v3.0 expression beadchip |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA128251 |
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