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Series GSE22792 Query DataSets for GSE22792
Status Public on Oct 20, 2010
Title Comparison of hiPSCs, hESCs and fibroblasts
Organism Homo sapiens
Experiment type Expression profiling by array
Summary In our study, PRDM14 and NFRkB were found to enhance the reprogramming of human fibroblasts to hiPSCs in the presence of OCT4, SOX2, KLF4, with/without c-MYC (OSK/OSKC). To examnie if the obtained hiPSC share similar expression signature with hESC, we conducted the microarray analysis on the hiPSCs, hESCs and fibroblasts. The result showed that all of the examined hiPSCs resembled hESCs, but differed from fibroblasts MRC5.
 
Overall design 4 hiPSC lines, 2 hESC lines and 1 type of fibroblasts were analyzed in total. Each sample is done in duplicates.
 
Contributor(s) Huck-Hui N, Feng B, Chia N
Citation(s) 20953172
Submission date Jul 07, 2010
Last update date Aug 16, 2018
Contact name NA-YU CHIA
Organization name Genome Institute of Singapore
Department STEM CELL 6
Lab NGHH
Street address 30 Biopolis Way
City SINGAPORE
ZIP/Postal code 138671
Country Singapore
 
Platforms (1)
GPL6947 Illumina HumanHT-12 V3.0 expression beadchip
Samples (14)
GSM563502 OSK+NFRKB hiPSC_rep1
GSM563503 OSK+NFRKB hiPSC_rep2
GSM563504 OSK+PRDM14 hiPSC_rep1
Relations
BioProject PRJNA127815

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE22792_RAW.tar 6.2 Mb (http)(custom) TAR
GSE22792_non_normalized.txt.gz 4.6 Mb (ftp)(http) TXT
Processed data included within Sample table

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