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Status |
Public on Oct 20, 2010 |
Title |
Comparison of hiPSCs, hESCs and fibroblasts |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
In our study, PRDM14 and NFRkB were found to enhance the reprogramming of human fibroblasts to hiPSCs in the presence of OCT4, SOX2, KLF4, with/without c-MYC (OSK/OSKC). To examnie if the obtained hiPSC share similar expression signature with hESC, we conducted the microarray analysis on the hiPSCs, hESCs and fibroblasts. The result showed that all of the examined hiPSCs resembled hESCs, but differed from fibroblasts MRC5.
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Overall design |
4 hiPSC lines, 2 hESC lines and 1 type of fibroblasts were analyzed in total. Each sample is done in duplicates.
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Contributor(s) |
Huck-Hui N, Feng B, Chia N |
Citation(s) |
20953172 |
Submission date |
Jul 07, 2010 |
Last update date |
Aug 16, 2018 |
Contact name |
NA-YU CHIA |
Organization name |
Genome Institute of Singapore
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Department |
STEM CELL 6
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Lab |
NGHH
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Street address |
30 Biopolis Way
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City |
SINGAPORE |
ZIP/Postal code |
138671 |
Country |
Singapore |
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Platforms (1) |
GPL6947 |
Illumina HumanHT-12 V3.0 expression beadchip |
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Samples (14)
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Relations |
BioProject |
PRJNA127815 |