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Series GSE22949 Query DataSets for GSE22949
Status Public on Oct 01, 2011
Title Cannabinoid Receptor 1 Dependent Effects of Isopropoyl dodeycl fluorophosphonate on Hepatic Gene Expression
Organism Mus musculus
Experiment type Expression profiling by array
Summary We tested the effects of isopropoyl dodecyl fluorophosphonate (IDFP) (10 mg/kg, i.p.), a pharmacological inhibitor of endocannabinoid degradation, on hepatic gene expression in mice. To determine if increased cannabinoid receptor 1 signaling is responsible for IDFP induced effects a subset of mice were pretreated with the cannabinoid receptor 1 antagonist (AM251) (10 mg/kg, i.p.).
Overall design Total RNA obtained from liver of mice treated with DMSO (n=6), IDFP (n=8), or AM251/IDFP (n=5) (all 10 mg/kg i.p.) for 4 hours.
Contributor(s) Ruby MA, Krauss RM
Citation(s) 22073164
Submission date Jul 15, 2010
Last update date Jun 14, 2018
Contact name Max Ruby
Organization name Children's Hospital Oakland Reserach Institue
Lab Krauss
Street address 5700 Martin Luther King Jr. Way
State/province CA
ZIP/Postal code 94609
Country USA
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (19)
GSM566584 IDFP1
GSM566585 IDFP2
GSM566586 IDFP3
BioProject PRJNA127797

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE22949_RAW.tar 3.1 Mb (http)(custom) TAR
GSE22949_non-normalized.txt.gz 3.1 Mb (ftp)(http) TXT
Raw data are available on Series record
Processed data included within Sample table

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