|
| Status |
Public on Nov 05, 2010 |
| Title |
Expression data from BAP1 depleted cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
The deubiquitinase BAP1 is a candidate tumor suppressor regulating cell proliferation in human and is required for development in Drosophila. BAP1 is assembled into high molecular weight transcriptional multi-protein complexes.
In order to identify potential BAP1 target genes, global mRNA expression profiling using microarrays was conducted.
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| |
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| Overall design |
U2OS cells, transfected with a non-target control shRNA or shRNAs targeting BAP1, were selected with puromycin containing medium and then synchronized at the G1/S border to allow comparative analysis of gene expression.
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| |
|
| Contributor(s) |
Yu H, Affar E |
| Citation(s) |
20805357 |
| Submission date |
Jul 20, 2010 |
| Last update date |
Mar 25, 2019 |
| Contact name |
El Bachir Affar |
| E-mail(s) |
el.bachir.affar@umontreal.ca
|
| Organization name |
Maisonneuve-Rosemont Hospital, University of Montreal
|
| Street address |
5415 boul. De l'Assomption
|
| City |
Montreal |
| State/province |
Quebec |
| ZIP/Postal code |
H1T 2M4 |
| Country |
Canada |
| |
|
| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
|
| Samples (9)
|
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| Relations |
| BioProject |
PRJNA131169 |
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