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Series GSE23541 Query DataSets for GSE23541
Status Public on May 30, 2012
Title Regulation of Embryonic and Induced Pluripotency by Aurora Kinase-p53 Signaling
Organism Mus musculus
Experiment type Expression profiling by array
Summary Illumina Beadchip array analyses of mouse embryonic stem cell gene expression profiles in the presence of or upon knockdown of Aurka. An ES complementation 'rescue' system was employed to measure the effects of knockdown (minus Dox). Aurka was rescued to wildtype levels in the presence of Dox (plus Dox). A control rescue ES cell line, with a Luciferase-targeting shRNA, was also assessed.
 
Overall design Total of 12 samples; Aurka_R (+/-Dox) and Control_R (+/-Dox); all performed in triplicates
 
Contributor(s) Lee D, Su J, Ang Y, Carvajal-Vergara X, Chang B, Sevilla A, Zhao R, Schaniel C, Mulero-Navarro S, Pereira C, Gingold J, Wang H, Zhao R, Darr H, Williamson A, Niu X, Aguilo F, Flores E, Sher Y, Hung M, Whetton A, Gelb B, Moore K, Snoeck H, Ma'ayan A, Lemischka I
Citation(s) 22862944
Submission date Aug 10, 2010
Last update date Jun 14, 2018
Contact name Yen-Sin Ang
Organization name Gladstone Institute, UCSF
Street address 1650 Owens Street
City san francisco
State/province CALIFORNIA
ZIP/Postal code 94158
Country USA
 
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (12)
GSM577213 Aurka_R_+Dox_rep1
GSM577214 Aurka_R_+Dox_rep2
GSM577215 Aurka_R_+Dox_rep3
Relations
BioProject PRJNA131833

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE23541_RAW.tar 3.1 Mb (http)(custom) TAR
GSE23541_non_normalized.txt.gz 3.7 Mb (ftp)(http) TXT
Processed data included within Sample table
Raw data are available on Series record

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