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Series GSE2392 Query DataSets for GSE2392
Status Public on Mar 10, 2005
Title Murine Rat Brain Injury
Organisms Mus musculus; Rattus norvegicus
Experiment type Expression profiling by array
Summary Summary: Brain trauma is a major cause of morbidity and mortality, both in adult and pediatric populations. Much of the functional deficit derives from delayed cell death resulting from induction of neurotoxic factors that overwhelm endogenous neuroprotective responses.
Hypothesis: Gene expression profiling across species and models may help identify candidate molecular pathways induced by brain injury, some of which may provide novel targets for therapeutic intervention.
Specific Aim: To identify the potential molecular mechanisms underlying such delayed responses, we compared gene expression patterns using high-density oligonucleotide arrays at 4, 8, 24 and 72 hours after moderate levels of lateral fluid percussion-induced brain injury in rats and lateral controlled cortical impact injury in mice.

Keywords: other
 
 
Contributor(s) Natale J
Citation(s) 14588109
Submission date Mar 09, 2005
Last update date Oct 01, 2019
Contact name Eric P Hoffman
E-mail(s) ericphoffman@gmail.com
Organization name Binghamton University - SUNY
Department Pharmaceutical Sciences
Street address PO Box 6000
City Binghamton
State/province NY
ZIP/Postal code 13902
Country USA
 
Platforms (2)
GPL81 [MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
GPL85 [RG_U34A] Affymetrix Rat Genome U34 Array
Samples (61)
GSM44463 JMR-MurInj24h-1cAv2-s2
GSM44464 JMR-MurInj24h-2cAv2-s2
GSM44465 JMR-MurInj4h-1aAv2-s2
Relations
BioProject PRJNA91203

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE2392_RAW.tar 161.2 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file

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