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| Status |
Public on Dec 07, 2010 |
| Title |
Gene expression profiles after traumatic brain injury |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
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| Summary |
Time dependent-profiles in the gene expression level following lateral moderate fluid percussion injury in the rat brain
We used microarray to elucidate relationship between the alteration of gene expression levels and the progression of brain damages following traumatic brain injury.
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| Overall design |
To examine the levels of gene expression in the early phase of traumatic brain injury, we analyzed the gene expression at 3, 6, 12, and 48 h after trauma using the lateral moderate fluid percussion TBI model. The ratios of the gene expression level were compared between chips corresponding to the 3, 6 and 12 h fluid percussion groups and the sham group chips. On the other hand, the rations of gene expression level after 48 h FPI were compared with 48 h sham chip, because the gene expression levels of 48 h sham chip were distinct from sham group chips (3, 6 and 12 h) in the cluster and principal components analyses.
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| Contributor(s) |
Shojo H |
| Citation(s) |
20950674, 28933223 |
| Submission date |
Sep 09, 2010 |
| Last update date |
Sep 12, 2019 |
| Contact name |
Hideki Shojo |
| E-mail(s) |
hshohjoh@yamanashi.ac.jp
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| Phone |
81-55-273-9546
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| Fax |
81-55-273-6753
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| Organization name |
University of Yamanashi
|
| Department |
Graduate School of Medical Science
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| Lab |
Department of Legal Medicine
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| Street address |
1110 shimokato
|
| City |
Chuo |
| State/province |
Yamanashi |
| ZIP/Postal code |
409-3898 |
| Country |
Japan |
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| Platforms (1) |
| GPL1355 |
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array |
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| Samples (16)
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| Relations |
| BioProject |
PRJNA130351 |
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