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| Status |
Public on Apr 01, 2011 |
| Title |
Mouse embryo heart, e10.5 AVC: Control vs. Tbx3 hypomorphic mutant |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Transcriptional profiling of the atrioventricular canal from e10.5 mouse hearts comparing wild-type control with Tbx3 GH/N hypomorphic mutant microdissected tissue.
The goal was to identify direct and indirect targets of the transcription factor Tbx3, because Tbx3 is expressed in the AVC and hypomorphs develop embryonic AV conduction block at e12.5.
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| Overall design |
Two-condition experiment, wild-type control and Tbx3 mutant AVC tissue. Tissue from 5 hearts was pooled to make each sample. Biological replicates: 4.
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| |
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| Contributor(s) |
Frank DU, Moon AM |
| Citation(s) |
22203979 |
| Submission date |
Sep 14, 2010 |
| Last update date |
May 10, 2018 |
| Contact name |
Deborah Frank |
| E-mail(s) |
deborah.frank@hsc.utah.edu
|
| Organization name |
University of Utah
|
| Department |
Pediatrics
|
| Lab |
Moon
|
| Street address |
15 North 2030 East
|
| City |
Salt Lake City |
| State/province |
UT |
| ZIP/Postal code |
84108 |
| Country |
USA |
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| Platforms (1) |
| GPL4134 |
Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Feature Number version) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA130061 |
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