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| Status |
Public on Sep 17, 2010 |
| Title |
Expression data from keratinocytes of WT and RASSF9-/- mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Mice with deficient expression of RASSF9 exhibit intriguing phenotypes of skin-related pathology, including abnormal thickening of the epidermis, dysregulated proliferation of keratinocytes, and alopecia.
To delineate the underlying mechanism, we profiled gene expression in keratinocytes of RASSF9-mutant mice to identify targets whose expressions were affected by RASSF9 gene deletion.
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| Overall design |
Primary keratinocytes from neonatal ICR mice of wildtype control (WT) or homozygous RASSF9 deletion (RASSF9-/-) were harvested for RNA extraction and hybridization on Affymetrix microarrays. For WT, a single microarray hybridization was performed. For RASSF9-/-, one hybridization was performed for each of two independent samples.
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| Contributor(s) |
Lee C, Chen L |
| Citation(s) |
21445300 |
| Submission date |
Sep 17, 2010 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Chiou-Mei Lee |
| E-mail(s) |
lcm5132@mail.cgu.edu.tw
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| Organization name |
Chang Gung Memorial Hospital
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| Department |
Department of Medical Research and Development
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| Street address |
5, Fusing St
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| City |
Kwei-Shan |
| State/province |
Taoyuan |
| ZIP/Postal code |
333 |
| Country |
Taiwan |
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| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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| Samples (3) |
| GSM595109 |
WT mouse keratinocytes |
| GSM595110 |
RASSF9-/- mouse keratinocytes (sample 1 of 2) |
| GSM595111 |
RASSF9-/- mouse keratinocytes (sample 2 of 2) |
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| Relations |
| BioProject |
PRJNA130157 |
