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Status |
Public on Aug 22, 2011 |
Title |
Gene expression data from liver of rat fed a high-fat diet and high-fructose water without/with Eucommia ulmoides leaves |
Organism |
Rattus norvegicus |
Experiment type |
Expression profiling by array
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Summary |
To investigate effects of intake of Eucommia ulmoides leaves on hyperlipidemia, we performed gene expression profiling on rat liver by microarray analysis. Microarray analysis revealed that Eucommia ulmoides leaves up-regulated the gene expression involved in alpha-, beta-, and omega-oxidation of fatty acids, mainly relating to peroxisome proliferator-activated receptor signaling pathway.
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Overall design |
Rats were fed a high-fat diet and high-fructose water without/with orally administration of Eucommia ulmoides leaves for 5 weeks. Livers were taken for RNA extraction and hybridization on Agilent microarrays.
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Contributor(s) |
Kobayashi Y, Hiroi T, Araki M, Hirokawa T, Miyazawa M, Aoki N, Kojima T, Ohsawa T |
Citation(s) |
21815167 |
Submission date |
Sep 27, 2010 |
Last update date |
Dec 21, 2016 |
Contact name |
Yukihiro Kobayashi |
E-mail(s) |
yukihiro@kaiyodai.ac.jp
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Organization name |
Tokyo University of Marine Science and Technology
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Department |
Department of Marine Biosciences
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Lab |
Laboratory of Aquatic Resource Utilization
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Street address |
4-5-7, Konan
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City |
Minato-ku |
State/province |
Tokyo |
ZIP/Postal code |
108-8477 |
Country |
Japan |
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Platforms (1) |
GPL4135 |
Agilent-014879 Whole Rat Genome Microarray 4x44K G4131F (Feature Number version) |
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Samples (8)
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Relations |
BioProject |
PRJNA132859 |