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| Status |
Public on Apr 09, 2005 |
| Title |
HIV-1 burden influences host response to co-infection with Neisseria gonorrhoeae in vitro |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Gene networks involved in HIV-1 infection of human PBMCs were investigated by dose dependant infection with HIV-1 (Bal). Perturbation of networks was evaluted using a co-infection with N. gonorrheae. Hierarchical clustering, fold change analysis, and contour mapping of genes was used to identify gene groups that were then anlayzed for statisically significant associations using EASE.
Keywords: dose response
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| Contributor(s) |
Montano M, Rarick M, Sebastiani P, Brinkmann P, Ericksen R, Skefos J |
| Citation(s) |
16352629 |
| Submission date |
Apr 06, 2005 |
| Last update date |
Dec 06, 2018 |
| Contact name |
Monty Montano |
| E-mail(s) |
mmontano@bu.edu
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| Phone |
617 414-4806
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| Fax |
617 414-3561
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| URL |
http://www.bmc.org/HIV-AIDS/MontyMontano.htm
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| Organization name |
Boston Medical Center
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| Department |
Medicine
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| Lab |
Center for HIV-1/AIDS Care and Research
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| Street address |
650 Albany Street, Bldg X, room 640
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| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02118 |
| Country |
USA |
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| Platforms (1) |
| GPL571 |
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array |
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| Samples (11)
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| GSM47700 |
High HIV-1 infection of human PBMCs in vitro, with N. gonorrheae (1) |
| GSM47862 |
High HIV-1 infection of human PBMCs in vitro, with N. gonorrheae (2) |
| GSM47863 |
Medium HIV-1 infection of human PBMCs in vitro, with N. gonorrheae (1) |
| GSM47864 |
Medium HIV-1 infection of human PBMCs in vitro, with N. gonorrheae (2) |
| GSM47865 |
Low HIV-1 infection of human PBMCs in vitro, with N. gonorrheae (1) |
| GSM47866 |
Low HIV-1 infection of human PBMCs in vitro, with N. gonorrheae (2) |
| GSM47867 |
High HIV-1 infection of human PBMCs in vitro, without N. gonorrheae (1) |
| GSM47868 |
High HIV-1 infection of human PBMCs in vitro, without N. gonorrheae (2) |
| GSM47869 |
Medium HIV-1 infection of human PBMCs in vitro, without N. gonorrheae (1) |
| GSM47870 |
Low HIV-1 infection of human PBMCs in vitro, without N. gonorrheae (1) |
| GSM47871 |
Low HIV-1 infection of human PBMCs in vitro, without N. gonorrheae (2) |
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| Relations |
| BioProject |
PRJNA92033 |
| Supplementary data files not provided |
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