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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Aug 30, 2013 |
| Title |
Expression profiling data of Mta1 from E9.0 mouse embryonic fibroblasts |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Mta1 gene expression reveals new targets and functions. Mta1 functions in p53 dependent and independent manner. Genes regulated by Mta1 in the presence and absence of p53 were indetified
This expression data contains 5 different samples (MEFs) 1.wild type 2. Mta1 knockout 3. Mta1 re-expression in the knock out MEFs 4. P53 knockout and 5. Mta1 over expression in P53 knock out MEFs. Various sample comparisons were done and genes with p-value< 0.05 and fold change ≥ 2.0 were considered statistically significant
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| Overall design |
5 samples (triplicates of each, total 15) were analyzed. We generated pairwise comparisons between the WT vs Mta1-KO; Mta1-KO vs Mta1-KO/Mta1; P53-KO vs P53-KO/Mta1.
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| Contributor(s) |
Ghanta KS, Kumar R |
| Citation(s) |
21364872 |
| Submission date |
Nov 01, 2010 |
| Last update date |
Mar 06, 2018 |
| Contact name |
krishna ghanta |
| Organization name |
GWU
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| Street address |
2300 eye st NW
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| City |
washington |
| State/province |
DC |
| ZIP/Postal code |
20037 |
| Country |
USA |
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| Platforms (1) |
| GPL6096 |
[MoEx-1_0-st] Affymetrix Mouse Exon 1.0 ST Array [transcript (gene) version] |
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| Samples (15)
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| GSM615962 |
Wildtype MEFs at E9.0,biological rep1 |
| GSM615963 |
Wildtype MEFs at E9.0,biological rep2 |
| GSM615964 |
Wildtype MEFs at E9.0,biological rep3 |
| GSM615965 |
Mta1 knockout at E9.0, biological rep1 |
| GSM615966 |
Mta1 knockout at E9.0, biological rep2 |
| GSM615967 |
Mta1 knockout at E9.0, biological rep3 |
| GSM615968 |
Mta1 reexpression in Knockout, rep1 |
| GSM615969 |
Mta1 reexpression in Knockout, rep2 |
| GSM615970 |
Mta1 reexpression in Knockout, rep3 |
| GSM615971 |
P53 knockout at E12.5, biological rep1 |
| GSM615972 |
P53 knockout at E12.5, biological rep2 |
| GSM615973 |
P53 knockout at E12.5, biological rep3 |
| GSM615974 |
Mta1 over expression in the P53 knockout,rep1 |
| GSM615975 |
Mta1 over expression in the P53 knockout,rep2 |
| GSM615976 |
Mta1 over expression in the P53 knockout,rep3 |
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| Relations |
| BioProject |
PRJNA134737 |
| Supplementary data files not provided |
| Processed data included within Sample table |
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